SCHEMBL538774

SCHEMBL538774

Cc1ccc([Al-](c2ccc(C)cc2C)(c2ccc(C)cc2C)c2ccc(C)cc2C)c(C)c1.c1ccc[cH+]cc1

nearest known ligand 0.34

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.34
TP53 P04637 1/20 0.34
ACHE P22303 1/20 0.31
CYP1A2 P05177 3/20 0.31
CYP2A6 P11509 3/20 0.31
CYP3A4 P08684 1/20 0.31
TSHR P16473 1/20 0.31
NPC1 O15118 1/20 0.30
LMNA P02545 1/20 0.30
NFKB1 P19838 1/20 0.30
RAB9A P51151 1/20 0.30
NFKB2 Q00653 1/20 0.30
RELA Q04206 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1450871 0.83 TDP1 (0.46) TDP1TP53ACHECYP1A2CYP2A6
SCHEMBL132865 0.81 TDP1 (0.44) TDP1TP53ACHECYP1A2CYP2A6
Potassium Ion SCHEMBL134597 0.81 TDP1 (0.44) TDP1TP53ACHECYP1A2CYP2A6
Lithium Ion SCHEMBL136411 0.81 TDP1 (0.44) TDP1TP53ACHECYP1A2CYP2A6
SCHEMBL7630008 0.78 HSD17B10 (0.39) TDP1ACHECYP3A4TSHRLMNA
SCHEMBL538837 0.76 TDP1 (0.38) TDP1TP53ACHECYP1A2CYP2A6
SCHEMBL538969 0.74 TDP1 (0.32) TDP1TP53ACHECYP2A6TSHR
SCHEMBL134188 0.73 TDP1 (0.34) TDP1TP53ACHECYP1A2CYP2A6
SCHEMBL30726900 0.73 TDP1 (0.34) TDP1TP53ACHECYP1A2CYP2A6
Diethylaniline SCHEMBL3898633 0.72 RAB9A (0.33) TDP1TP53CYP2A6NPC1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 225 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3239190-A2 POLYMERIZATION CATALYSTS FOR PRODUCING POLYMERS WITH LOW LEVELS OF LONG CHAIN BRANCHING Chevron Phillips Chemical Company LP (US) 2017-11-01 EP claimed
EP-1706437-B1 DUAL METALLOCENE CATALYST FOR PRODUCING FILM RESINS WITH GOOD MACHINE DIRECTION (MD) ELMENDORF TEAR STRENGTH CHEVRON PHILLIPS CHEMICAL CO (US) 2016-01-20 EP claimed
EP-1711543-B1 CATALYST COMPOSITIONS AND POLYOLEFINS FOR EXTRUSION COATING APPLICATIONS CHEVRON PHILLIPS CHEMICAL CO (US) 2011-08-24 EP claimed
EP-2010577-B1 POLYMERIZATION CATALYSTS FOR PRODUCING POLYMERS WITH LOW LEVELS OF LONG CHAIN BRANCHING CHEVRON PHILLIPS CHEMICAL CO (US) 2010-11-17 EP claimed
US-7619047-B2 Dual metallocene catalysts for polymerization of bimodal polymers CHEVRON PHILLIPS CHEMICAL COMPANY, LP (US) 2009-11-17 US claimed
US-7576163-B2 Polymerization catalysts for producing polymers with low levels of long chain branching CHEVRON PHILLIPS CHEMICAL COMPANY, LP (US) 2009-08-18 US claimed
US-7517939-B2 Polymerization catalysts for producing high molecular weight polymers with low levels of long chain branching CHEVRON PHILLIPS CHEMICAL COMPANY, LP (US) 2009-04-14 US claimed
EP-1773899-B1 POLYMERIZATION CATALYSTS FOR PRODUCING POLYMERS WITH LOW LEVELS OF LONG CHAIN BRANCHING CHEVRON PHILLIPS CHEMICAL CO (US) 2009-02-11 EP claimed
EP-2010577-A2 POLYMERIZATION CATALYSTS FOR PRODUCING POLYMERS WITH LOW LEVELS OF LONG CHAIN BRANCHING Chevron Phillips Chemical Company LP (US) 2009-01-07 EP claimed
EP-1989238-A1 DUAL METALLOCENE CATALYSTS FOR POLYMERIZATION OF BIMODAL POLYMERS Chevron Phillips Chemical Company LP (US) 2008-11-12 EP claimed
US-6982306-B2 Stannoxy-substituted metallocene catalysts for olefin and acetylene polymerization CHEVRON PHILLIPS CHEMICAL COMPANY, L.P. (US) 2006-01-03 US claimed
US-20050288462-A1 Polymerization catalysts for producing polymers with low levels of long chain branching CHEVRON PHILIPS CHEMICAL COMPANY, L.P. 2005-12-29 US claimed
US-20050288461-A1 Polymerization catalysts for producing polymers with low levels of long chain branching CHEVRON PHILLIPS CHEMICAL COMPANY, L.P. 2005-12-29 US claimed
WO-2005070977-A1 DUAL METALLOCENE CATALYST FOR PRODUCING FILM RESINS WITH GOOD MACHINE DIRECTION (MD) ELMENDORF TEAR STRENGTH CHEVRON PHILLIPS CHEMICAL COMPANY, LP (US) 2005-08-04 WO claimed
WO-2005068519-A2 CATALYST COMPOSITIONS AND POLYOLEFINS FOR EXTRUSION COATING APPLICATIONS CHEVRON PHILLIPS CHEMICAL COMPANY, LP (US) 2005-07-28 WO claimed
US-20050159300-A1 Dual metallocene catalyst for producing film resins with good machine direction (MD) elmendorf tear strength CHEVRON PHILLIPS CHEMICAL COMPANY LP 2005-07-21 US claimed
US-20050153830-A1 contact product of a first metallocene compound, a second metallocene compound, a chemically-treated solid oxide, and an organoaluminum compound; useful properties in impact, tear, adhesion, sealing, extruder motor loads and pressures at comparable melt index values, and neck-in and draw-down. CHEVRON PHILIPS CHEMICAL COMPANY LP 2005-07-14 US claimed
WO-2005052011-A1 CATALYST COMPOSITIONS FOR PRODUCING POLYOLEFINS IN THE ABSENCE OF COCATALYSTS CHEVRON PHILLIPS CHEMICAL COMPANY, LP (US) 2005-06-09 WO claimed
US-20050113243-A1 Catalyst compositions for producing polyolefins in the absence of cocatalysts CHEVRON PHILLIPS CHEMICAL COMPANY, LP 2005-05-26 US claimed
US-20050113245-A1 STANNOXY-SUBSTITUTED METALLOCENE CATALYSTS FOR OLEFIN AND ACETYLENE POLYMERIZATION CHEVRON PHILLIPS CHEMICAL COMPANY LP 2005-05-26 US claimed