Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 4/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | CTSB | P07858 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | PLAU | P00749 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CTSD | P07339 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nitrophenolate SCHEMBL22033631 | 0.95 | GPR35 (0.61) | GPR35MAPK1HSD17B10CTSBALOX15 | |
| Nitrophenolate SCHEMBL26026 | 0.95 | GPR35 (0.65) | GPR35MAPK1HSD17B10CTSBALOX15 | |
| Nitrophenolate SCHEMBL29360402 | 0.95 | GPR35 (0.65) | GPR35MAPK1HSD17B10CTSBALOX15 | |
| Nitrophenolate SCHEMBL28029048 | 0.95 | GPR35 (0.65) | GPR35MAPK1HSD17B10CTSBALOX15 | |
| Nitrophenolate SCHEMBL11344901 | 0.93 | GPR35 (0.63) | GPR35MAPK1HSD17B10CTSBALOX15 | |
| Nitrophenolate SCHEMBL31063576 | 0.93 | GPR35 (0.63) | GPR35MAPK1HSD17B10CTSBALOX15 | |
| Nitrophenolate SCHEMBL325409 | 0.93 | GPR35 (0.63) | GPR35MAPK1HSD17B10CTSBALOX15 | |
| Nitrophenolate SCHEMBL10996867 | 0.93 | GPR35 (0.63) | GPR35MAPK1HSD17B10CTSBALOX15 | |
| Nitrophenolate SCHEMBL10496084 | 0.93 | GPR35 (0.63) | GPR35MAPK1HSD17B10CTSBALOX15 | |
| Nitrophenolate SCHEMBL16553333 | 0.93 | GPR35 (0.63) | GPR35MAPK1HSD17B10CTSBALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1448791-B1 | METHOD FOR DETECTING CATALYTIC ACTIVITY | PROTEUS (FR) | 2006-08-09 | — | — | EP | claimed |
| US-7238483-B2 | Method for detecting catalytic activity | PROTEUS SA (FR) | 2007-07-03 | — | — | US | disclosed |
| US-20050014212-A1 | Method for detecting catalytic activity | PROTEUS (FR) | 2005-01-20 | — | — | US | disclosed |