Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 2/20 | 0.60 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.60 |
| ▸ | PGK1 | P00558 | 4/20 | 0.56 |
| ▸ | PGK2 | P07205 | 4/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.54 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.54 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.52 |
| ▸ | NT5E | P21589 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6257693 | 0.92 | ADORA2A (0.71) | ADORA2BADORA2APGK1PGK2ADORA3 | |
| SCHEMBL7083928 | 0.84 | ADORA2A (0.74) | ADORA2BADORA2APGK1PGK2ADORA3 | |
| SCHEMBL5389218 | 0.84 | ADORA2A (0.74) | ADORA2BADORA2APGK1PGK2ADORA3 | |
| SCHEMBL4806899 | 0.81 | PGK1 (0.85) | ADORA2BPGK1PGK2ADORA3ADORA1 | |
| SCHEMBL5393072 | 0.80 | ADORA3 (0.77) | ADORA2BADORA2AADORA3ADORA1 | |
| SCHEMBL5389657 | 0.80 | ADORA3 (0.77) | ADORA2BADORA2AADORA3ADORA1 | |
| SCHEMBL6262523 | 0.79 | ADORA1 (0.71) | ADORA2BADORA2APGK1PGK2ADORA3 | |
| SCHEMBL5386790 | 0.79 | ADORA1 (0.71) | ADORA2BADORA2APGK1PGK2ADORA3 | |
| SCHEMBL6262513 | 0.79 | ADORA1 (0.71) | ADORA2BADORA2APGK1PGK2ADORA3 | |
| SCHEMBL5392594 | 0.78 | ADORA2A (0.70) | ADORA2BADORA2APGK1PGK2ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7262176-B2 | Adenosine A3 receptor agonists | CV THERAPEUTICS, INC. (US) | 2007-08-28 | — | — | US | disclosed |
| US-20040116376-A1 | Adenosine A3 receptor agonists | CV THERAPEUTICS, INC. | 2004-06-17 | — | — | US | disclosed |