Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5389054 | 0.91 | MEN1 (0.39) | MEN1KMT2APKMHTTALDH1A1 | |
| SCHEMBL5394055 | 0.88 | PKM (0.40) | MEN1KMT2APKMHTTALDH1A1 | |
| SCHEMBL7774902 | 0.76 | RAB9A (0.50) | MEN1KMT2APKMHTTALDH1A1 | |
| SCHEMBL5983929 | 0.76 | TDP1 (0.36) | MEN1KMT2ANPSR1RECQLLTA4H | |
| SCHEMBL7772783 | 0.74 | FYN (0.43) | MEN1KMT2APKMHTTALDH1A1 | |
| SCHEMBL5400790 | 0.71 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL8783166 | 0.70 | ABCG2 (0.39) | MEN1KMT2APKMHTTALDH1A1 | |
| SCHEMBL7053357 | 0.62 | PKM (0.59) | MEN1KMT2APKMHTTALDH1A1 | |
| SCHEMBL5394050 | 0.62 | TDP1 (0.40) | MEN1KMT2ARAB9ALTA4HSLC6A3 | |
| SCHEMBL5389044 | 0.61 | ESR1 (0.32) | MEN1KMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1660463-A1 | A PROCESS FOR THE PREPARATION OF PHENYLTETRAZOLE DERIVATIVES | Dipharma S.p.A. (IT) | 2006-05-31 | — | — | EP | disclosed |
| WO-2005014560-A1 | A PROCESS FOR THE PREPARATION OF PHENYLTETRAZOLE DERIVATIVES | DIPHARMA S.P.A. (IT) | 2005-02-17 | — | — | WO | disclosed |