Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.63 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | CES1 | P23141 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | CA1 | P00915 | 2/20 | 0.55 |
| ▸ | CA2 | P00918 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL254773 | 0.88 | CES1 (0.65) | MAPK1POLBCES1KMT2AMEN1 | |
| SCHEMBL27616736 | 0.87 | MAPK1 (0.79) | MAPK1POLBCES1KMT2AMEN1 | |
| Methylamine SCHEMBL29169653 | 0.87 | TSHR (0.60) | MAPK1POLBCES1KMT2AMEN1 | |
| SCHEMBL27847800 | 0.86 | MAPK1 (0.63) | MAPK1CES1KMT2AMEN1CA1 | |
| SCHEMBL1312520 | 0.84 | MAPK1 (0.58) | MAPK1POLBCES1KMT2AMEN1 | |
| SCHEMBL12275941 | 0.84 | ACHE (0.64) | MAPK1POLBCES1KMT2AMEN1 | |
| SCHEMBL2764169 | 0.83 | MAPK1 (0.56) | MAPK1POLBCES1KMT2AMEN1 | |
| SCHEMBL7297654 | 0.82 | CES1 (0.53) | MAPK1POLBCES1KMT2AMEN1 | |
| SCHEMBL8759338 | 0.82 | MAPK1 (0.59) | MAPK1POLBCES1KMT2AMEN1 | |
| SCHEMBL27866766 | 0.82 | POLB (0.62) | MAPK1POLBCES1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0239194-A2 | Methods for preparing hydroxy compounds and intermediates | SYMBICOM AB (SE) | 1987-09-30 | — | — | EP | claimed |
| EP-3614113-B1 | TEMPERATURE DETECTING MATERIAL AND PRODUCT CONTROL METHOD | HITACHI INDUSTRY EQUIPMENT SYSTEMS CO LTD (JP) | 2024-07-17 | — | — | EP | disclosed |
| CN-117836596-A | Temperature indicator manufacturing system and temperature indicator manufacturing method | 株式会社日立产机系统 | 2024-04-05 | — | — | CN | disclosed |
| US-11933677-B2 | Temperature detecting material, temperature detecting ink using same, temperature indicator, and product control system | HITACHI INDUSTRIAL EQUIPMENT SYSTEMS CO., LTD. (JP) | 2024-03-19 | — | — | US | disclosed |
| CN-109511264-B | Polymethine compounds | 株式会社艾迪科 | 2021-06-08 | — | — | CN | disclosed |
| CN-111602041-A | Temperature detection ink, method for initializing temperature detection ink, temperature indicator, and article management system | 株式会社日立产机系统 | 2020-08-28 | — | — | CN | disclosed |
| CN-111433577-A | Temperature detection label and article management device using same | 株式会社日立制作所 | 2020-07-17 | — | — | CN | disclosed |
| EP-3614113-A1 | TEMPERATURE DETECTION MATERIAL, TEMPERATURE DETECTION INK USING SAME, TEMPERATURE INDICATOR, AND ARTICLE MANAGEMENT SYSTEM | HITACHI INDUSTRIAL EQUIPMENT SYSTEMS CO., LTD. (JP) | 2020-02-26 | — | — | EP | disclosed |
| US-20200041359-A1 | Temperature Detecting Material, Temperature Detecting Ink Using Same, Temperature Indicator, and Product Control System | HITACHI INDUSTRIAL EQUIPMENT SYSTEMS CO., LTD. (JP) | 2020-02-06 | — | — | US | disclosed |
| WO-2019142485-A1 | TEMPERATURE DETECTION LABEL AND ARTICLE MANAGEMENT DEVICE USING SAME | 株式会社日立製作所 | 2019-07-25 | — | — | WO | disclosed |
| EP-2792694-A1 | CURABLE RESIN COMPOSITION | Three Bond Fine Chemical Co., Ltd. (JP) | 2014-10-22 | — | — | EP | disclosed |
| US-7217730-B2 | Method for the use of pyranoindole derivatives to treat infection with Hepatitis C virus | WYETH (US) | 2007-05-15 | — | — | US | disclosed |
| EP-1509225-A1 | METHOD FOR THE USE OF PYRANOINDOLE DERIVATIVES TO TREAT INFECTION WITH HEPATITIS C VIRUS | Wyeth (US) | 2005-03-02 | — | — | EP | disclosed |
| US-20040082643-A1 | Method for the use of pyranoindole derivatives to treat infection with Hepatitis C virus | WYETH (US) | 2004-04-29 | — | — | US | disclosed |
| WO-2003099275-A1 | METHOD FOR THE USE OF PYRANOINDOLE DERIVATIVES TO TREAT INFECTION WITH HEPATITIS C VIRUS | WYETH (US) | 2003-12-04 | — | — | WO | disclosed |
| US-6139946-A | Magnetic recording media incorporating a quaternary ammonium functional binder and magnetic pigment surface treated with compound having acidic and electron withdrawing functionalities | IMATION CORP. (US) | 2000-10-31 | — | — | US | disclosed |
| CN-1160398-A | Compositions and methods for treating mast-cell inflammatory condition | ARRIS PHARM CORP (US) | 1997-09-24 | — | — | CN | disclosed |
| US-4871837-A | DEPROTECTING SILYL-PROTECTED CARBOHYDRATES, AMINO ACIDS, PEPTIDES; LEWIS ACID HYDROLYSIS | SYMBICOM AKTIEBOLAG (SE) | 1989-10-03 | — | — | US | disclosed |
| EP-0239194-A2 | Methods for preparing hydroxy compounds and intermediates | SYMBICOM AB (SE) | 1987-09-30 | — | — | EP | disclosed |
| US-3932182-A | An organic photoconductive composition comprising an organic photoconductive compound and a sensitizing compound having an active methylene group | MITSUBISHI PAPER MILLS, LTD. (JA) | 1976-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040082643-A1 | Method for the use of pyranoindole derivatives to treat infection with Hepatitis C virus | HAVCR2, HCCS, ZC3HAV1 | MAPK1 2864/4885POLB 4428/4885CES1 171/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.