Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 2/20 | 0.65 |
| ▸ | CA1 | P00915 | 2/20 | 0.63 |
| ▸ | CA2 | P00918 | 2/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.57 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.57 |
| ▸ | CES2 | O00748 | 1/20 | 0.57 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.57 |
| ▸ | GSK3B | P49841 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methylamine SCHEMBL29169653 | 0.94 | TSHR (0.60) | CES1CA1CA2TDP1ALDH1A1 | |
| SCHEMBL254774 | 0.92 | CES1 (0.70) | CES1CA1CA2TDP1ALDH1A1 | |
| SCHEMBL27616736 | 0.91 | MAPK1 (0.79) | CES1CA1CA2TDP1ALDH1A1 | |
| SCHEMBL8674798 | 0.91 | KMT2A (0.65) | CES1CA1CA2TDP1ALDH1A1 | |
| SCHEMBL12275941 | 0.91 | ACHE (0.64) | CES1CA1CA2TDP1ALDH1A1 | |
| Methane SCHEMBL28800504 | 0.91 | CES1 (0.68) | CES1CA1CA2TDP1ALDH1A1 | |
| SCHEMBL11527673 | 0.88 | CES1 (0.57) | CES1CA1CA2TDP1ALDH1A1 | |
| SCHEMBL4399328 | 0.88 | ALDH1A1 (0.63) | CES1CA1CA2TDP1ALDH1A1 | |
| SCHEMBL5389258 | 0.88 | MAPK1 (0.63) | CES1CA1CA2TDP1ALDH1A1 | |
| SCHEMBL11527677 | 0.88 | TSHR (0.63) | CES1CA1CA2TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 277 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118126530-B | Low-dielectric-constant polyphenylene sulfide material for millimeter waves and preparation method thereof | 江西聚真科技发展有限公司 | 2024-12-17 | — | — | CN | claimed |
| CN-112441984-B | Benzimidazole-substituted phenyl n-butyramide-based compound and preparation method thereof | 上海特化医药科技有限公司 | 2024-04-19 | — | — | CN | claimed |
| CN-117003740-A | Synthesis method of 1N-methyl pseudouridine derivative | 江苏申基生物科技有限公司 | 2023-11-07 | — | — | CN | claimed |
| CN-116410145-A | Preparation method of MRTX849 intermediate | 上海泓博智源医药股份有限公司 | 2023-07-11 | — | — | CN | claimed |
| CN-116120335-A | Curcumenol derivative as Wnt signal pathway agonist and preparation method and application thereof | 国科大杭州高等研究院 | 2023-05-16 | — | — | CN | claimed |
| CN-115894380-A | N-aryl substituted imino ester compound and preparation method and application thereof | 上海特化医药科技有限公司 | 2023-04-04 | — | — | CN | claimed |
| CN-113330017-B | Purification method and application of SGLTs inhibitor | 上海研健新药研发有限公司 | 2023-01-31 | — | — | CN | claimed |
| CN-115073534-A | Synthetic method of emamectin benzoate | 吴晓明 | 2022-09-20 | — | — | CN | claimed |
| US-20220289684-A1 | BENZIMIDAZOLE SUBSTITUTION-BASED PHENYL N-BUTYRAMIDE COMPOUND AND PREPARATION METHOD THEREFOR | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2022-09-15 | — | — | US | claimed |
| CN-111349238-B | Polyetherimide and preparation process thereof | 万华化学集团股份有限公司 | 2022-08-05 | — | — | CN | claimed |
| CN-110684517-A | Self-polymerization consolidation compression-resistant permeation-increasing temperature-resistant sand control agent | 四川捷贝通能源科技有限公司 | 2020-01-14 | — | — | CN | claimed |
| US-20180273819-A1 | THERMAL ENERGY STORAGE PHASE AND TEMPERATURE STABILIZATION CHANGE MATERIALS COMPRISING TRIAMINES AND METHODS FOR MAKING AND USING THEM | ENTROPY SOLUTIONS LLC (US) | 2018-09-27 | — | — | US | claimed |
| WO-2016179028-A1 | THERMAL ENERGY STORAGE PHASE AND TEMPERATURE STABILIZATION CHANGE MATERIALS AND METHODS FOR MAKING AND USING THEM | ENTROPY SOLUTIONS, LLC. (US) | 2016-11-10 | — | — | WO | claimed |
| EP-2841417-A1 | SYNTHESIS OF LACTAMS | Tavares, Francis Xavier (US) | 2015-03-04 | — | — | EP | claimed |
| WO-2013163239-A1 | SYNTHESIS OF LACTAMS | TAVARES FRANCIS XAVIER (US) | 2013-10-31 | — | — | WO | claimed |
| CN-100475772-C | Tech. of preparing amino benz methyl-phenoxide by nitro methyl-phenoxide mixture catalyzing hydrogenation | CHANGZHOU JISEN CHEMICAL CO LT (CN) | 2009-04-08 | — | — | CN | claimed |
| CN-100361957-C | Tech. of preparing 2,4-di nitro methyl-phenoxide by nitro methyl-phenoxide continuous thermal insulating nitration | JIASEN CHEMICAL INDUSTRY CO LT (CN) | 2008-01-16 | — | — | CN | claimed |
| CN-1861564-A | Tech. of preparing 2,4-di nitro methyl-phenoxide by nitro methyl-phenoxide continuous thermal insulating nitration | JIASEN CHEMICAL INDUSTRY CO LT (CN) | 2006-11-15 | — | — | CN | claimed |
| CN-1861570-A | Tech. of preparing amino benz methyl-phenoxide by nitro methyl-phenoxide mixture catalyzing hydrogenation | JISEN CHEMICAL INDUSTRY CO LTD (CN) | 2006-11-15 | — | — | CN | claimed |
| EP-0239194-A2 | Methods for preparing hydroxy compounds and intermediates | SYMBICOM AB (SE) | 1987-09-30 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220289684-A1 | BENZIMIDAZOLE SUBSTITUTION-BASED PHENYL N-BUTYRAMIDE COMPOUND AND PREPARATION METHOD THEREFOR | PAH, PNP, CYP3A4 | CES1 2989/4885CA1 4107/4885CA2 1434/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.