Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | CES1 | P23141 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | CA1 | P00915 | 2/20 | 0.57 |
| ▸ | CA2 | P00918 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.52 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL254773 | 0.94 | CES1 (0.65) | TSHRMAPK1CES1KMT2APKM | |
| Methyl Carbamate SCHEMBL28555184 | 0.90 | POLB (0.60) | TSHRMAPK1CES1KMT2APKM | |
| SCHEMBL27616736 | 0.89 | MAPK1 (0.79) | TSHRMAPK1CES1KMT2APKM | |
| SCHEMBL12275941 | 0.89 | ACHE (0.64) | TSHRMAPK1CES1KMT2APKM | |
| SCHEMBL5389258 | 0.87 | MAPK1 (0.63) | TSHRMAPK1CES1KMT2APKM | |
| SCHEMBL11527677 | 0.87 | TSHR (0.63) | TSHRMAPK1CES1KMT2APKM | |
| SCHEMBL254774 | 0.87 | CES1 (0.70) | TSHRMAPK1CES1KMT2APOLB | |
| SCHEMBL8674798 | 0.85 | KMT2A (0.65) | TSHRMAPK1CES1KMT2APKM | |
| Methane SCHEMBL28800504 | 0.85 | CES1 (0.68) | TSHRMAPK1CES1KMT2APOLB | |
| SCHEMBL7727851 | 0.84 | ALDH1A1 (0.56) | TSHRMAPK1CES1KMT2APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112771027-B | Lysophosphatidic acid receptor antagonists and process for preparing the same | 武汉朗来科技发展有限公司 | 2024-03-05 | — | — | CN | disclosed |