SCHEMBL538994

SCHEMBL538994

CCCOc1ccc(C(=O)O)c(O)c1

nearest known ligand 0.61

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.55
MAOB P27338 6/20 0.55
PPARD Q03181 1/20 0.55
HTT P42858 1/20 0.53
CA12 O43570 1/20 0.52
ALDH1A1 P00352 1/20 0.52
CA1 P00915 1/20 0.52
CA2 P00918 1/20 0.52
TSHR P16473 1/20 0.52
CA7 P43166 1/20 0.52
CA9 Q16790 1/20 0.52
CA14 Q9ULX7 1/20 0.52
MCL1 Q07820 1/20 0.51
LTA4H P09960 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL538636 0.93 PPARD (0.58) MAOBPPARDTSHRMCL1
SCHEMBL6297038 0.92 PPARD (0.57) MAOBPPARDTSHRMCL1
SCHEMBL3160539 0.90 PTPN11 (0.60) MAOBPPARDTSHRMCL1
SCHEMBL3161292 0.89 PTPN11 (0.63) MAOBTSHR
SCHEMBL10421190 0.89 PTPN11 (0.63) MAOBTSHR
SCHEMBL1374907 0.89 PTPN11 (0.63) MAOBTSHR
SCHEMBL1373719 0.89 PTPN11 (0.63) MAOBTSHR
SCHEMBL1374367 0.89 PTPN11 (0.63) MAOBTSHR
SCHEMBL1376266 0.89 PTPN11 (0.63) MAOBTSHR
SCHEMBL1377668 0.89 PTPN11 (0.63) MAOBTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 136 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3389595-B1 COMBINATION OF POLYION COMPLEX PARTICLE AND NON-POLYMERIC ACID HAVING TWO OR MORE ACID DISSOCIATION CONSTANTS OREAL (FR) 2025-11-05 EP disclosed
EP-3638192-B1 COMBINATION OF POLYION COMPLEX PARTICLE AND NON-POLYMERIC ACID OR BASE HAVING TWO OR MORE DISSOCIATION CONSTANTS OREAL (FR) 2025-04-02 EP disclosed
EP-3638201-B1 COMBINATION OF POLYION COMPLEX PARTICLE AND NON-POLYMERIC BASE HAVING TWO OR MORE DISSOCIATION CONSTANTS OREAL (FR) 2025-02-26 EP disclosed
WO-2024214568-A1 WATER-BASED COSMETIC 株式会社 資生堂 2024-10-17 WO disclosed
US-12029303-B2 Method for preparation of a cosmetic kit SHISEIDO COMPANY, LTD. (JP) 2024-07-09 US disclosed
CN-110446488-B Two-dose cosmetic 株式会社资生堂 2024-07-02 CN disclosed
WO-2024135300-A1 COSMETIC COMPOSITION, COSMETIC COMPOSITION FOR SUPPRESSING DISCOLORATION, AND DISCOLORATION SUPPRESSANT 株式会社資生堂 2024-06-27 WO disclosed
US-11975093-B2 Composition comprising oil and polyion complex including cellulose-based cationic polymer with at least one fatty chain L'OREAL (FR) 2024-05-07 US disclosed
WO-2024090247-A1 BEAUTY COMPOSITION, BEAUTY METHOD, AND AGENT FOR PROMOTING SKIN PERMEABILITY OF ALKOXY SALICYLIC ACID OR SALT THEREOF 株式会社 資生堂 2024-05-02 WO disclosed
EP-3597174-B1 TWO-COMPONENT COSMETIC SHISEIDO CO LTD (JP) 2024-04-17 EP disclosed
WO-2006105261-A1 CLEANSING COMPOSITIONS WITH COLOR CHANGING INDICATOR C2C TECHNOLOGIES LLC (US) 2006-10-05 WO disclosed
WO-2006105193-A2 PERSONAL CARE COMPOSITIONS WITH COLOR CHANGING INDICATOR C2C TECHNOLOGIES LLC (US) 2006-10-05 WO disclosed
US-20060222675-A1 Personal care compositions with color changing indicator C2C TECHNOLOGIES, LLC 2006-10-05 US disclosed
US-20060222601-A1 Oral care compositions with color changing indicator C2C TECHNOLOGIES, LLC 2006-10-05 US disclosed
EP-1563831-A1 EXTERNAL COMPOSITION FOR SKIN Shiseido Co., Ltd. (JP) 2005-08-17 EP disclosed
CN-1636550-A Water-in-oil emulsion composition SHISEIDO CO LTD (JP) 2005-07-13 CN disclosed
CN-1636549-A Oil-in-water emulsion composition SHISEIDO CO LTD (JP) 2005-07-13 CN disclosed
EP-0570230-B1 External preparation for skin SHISEIDO CO LTD (JP) 1998-09-30 EP disclosed
US-5580549-A BLEACHING; 2-HYDROXYBENZOIC ACID COMPOUND SHISEIDO CO., LTD. (JP) 1996-12-03 US disclosed
EP-0570230-A1 External preparation for skin SHISEIDO COMPANY LIMITED (JP) 1993-11-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060222675-A1 Personal care compositions with color changing indicator CUTA, POLR1C, TYR KMT2A 3653/4885MAOB 2876/4885PPARD 680/4885
US-11975093-B2 Composition comprising oil and polyion complex including cellulose-based cationic polymer with at least one fatty chain PRKCA, PRKCH, CUTA KMT2A 1749/4885MAOB 3381/4885PPARD 3282/4885
US-20060222601-A1 Oral care compositions with color changing indicator CA9, CA7, TAS2R7 KMT2A 2738/4885MAOB 3804/4885PPARD 2244/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.