Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Nitric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | CRHBP | P24387 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.30 |
| ▸ | MGLL | Q99685 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15261003 | 0.79 | — | — | |
| Nitric Acid SCHEMBL813725 | 0.77 | CA5A (0.44) | CA5ACA5BTSHRALDH1A1HCAR3 | |
| Nitric Acid SCHEMBL8193567 | 0.75 | — | — | |
| SCHEMBL8350870 | 0.74 | ALDH1A1 (0.36) | TSHRALDH1A1 | |
| SCHEMBL28216548 | 0.73 | — | — | |
| Butane SCHEMBL7161573 | 0.73 | CA5A (0.61) | CA5ACA5BTSHRALDH1A1 | |
| Butane SCHEMBL18261807 | 0.73 | — | — | |
| SCHEMBL4961720 | 0.70 | — | — | |
| Butane SCHEMBL11144889 | 0.70 | — | — | |
| Nitric Acid SCHEMBL27957404 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1618618-A4 | IONIC LIQUIDS AND IONIC LIQUID ACIDS WITH HIGH TEMPERATURE STABILITY FOR FUEL CELL AND OTHER HIGH TEMPERATURE APPLICATIONS, METHOD OF MAKING AND CELL EMPLOYING SAME | UNIV ARIZONA (US) | 2007-12-19 | — | — | EP | claimed |
| US-20070026295-A1 | Ionic liquids & ionic liquid acids with high temperature stability for fuel cell and other high temperature applications, method of making and cell employing same | UNITED STATES DEPARTMENT OF ENERGY | 2007-02-01 | — | — | US | claimed |
| JP-2007500429-A | — | — | 2007-01-11 | — | — | JP | claimed |
| EP-1618618-A1 | IONIC LIQUIDS AND IONIC LIQUID ACIDS WITH HIGH TEMPERATURE STABILITY FOR FUEL CELL AND OTHER HIGH TEMPERATURE APPLICATIONS, METHOD OF MAKING AND CELL EMPLOYING SAME | Arizona Board of Regents (US) | 2006-01-25 | — | — | EP | claimed |
| WO-2004114445-A1 | IONIC LIQUIDS AND IONIC LIQUID ACIDS WITH HIGH TEMPERATURE STABILITY FOR FUEL CELL AND OTHER HIGH TEMPERATURE APPLICATIONS, METHOD OF MAKING AND CELL EMPLOYING SAME | ARIZONA BOARD OF REGENTS A BODY CORPORATE ACTING ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2004-12-29 | — | — | WO | claimed |