Acetamide

Acetamide

SCHEMBL539092

CC(N)=O.Cc1ccccc1S(=O)(=O)c1ccccc1C

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.50
ALDH1A1 P00352 3/20 0.50
HSD11B1 P28845 1/20 0.46
SLC1A3 P43003 1/20 0.45
SLC1A2 P43004 1/20 0.45
SLC1A1 P43005 1/20 0.45
GAA P10253 1/20 0.45
POLB P06746 3/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
ABCC9 O60706 1/20 0.43
ABCC8 Q09428 1/20 0.43
KCNJ11 Q14654 1/20 0.43
KCNJ8 Q15842 1/20 0.43
MCOLN3 Q8TDD5 2/20 0.42
MAPT P10636 1/20 0.41
HTT P42858 1/20 0.41
MEN1 O00255 1/20 0.41
HPGD P15428 1/20 0.41
KMT2A Q03164 1/20 0.41
CA1 P00915 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL475089 0.87 ALDH1A1 (0.55) KDM4EALDH1A1HSD11B1GAAPOLB
SCHEMBL29468592 0.87 ALDH1A1 (0.55) KDM4EALDH1A1HSD11B1GAAPOLB
Acetamide SCHEMBL5102675 0.86 MYC (0.46) KDM4EALDH1A1HSD11B1SLC1A3SLC1A2
SCHEMBL3641319 0.85 ALDH1A1 (0.45) KDM4EALDH1A1HSD11B1SLC1A3SLC1A2
Acetone SCHEMBL27554717 0.81 HSD11B1 (0.49) KDM4EALDH1A1HSD11B1POLBL3MBTL1
O-Xylene SCHEMBL8469340 0.79 TSHR (0.59) KDM4EALDH1A1GAAPOLBL3MBTL1
Urea SCHEMBL9957182 0.79 CA1 (0.51) SLC1A3SLC1A2SLC1A1CA1CA2
Acetone SCHEMBL8415211 0.79 CA1 (0.51) ALDH1A1SLC1A3SLC1A2SLC1A1POLB
SCHEMBL6916212 0.79 GAA (0.75) KDM4EALDH1A1HSD11B1GAAPOLB
SCHEMBL27623150 0.78 ALDH1A1 (0.49) KDM4EALDH1A1HSD11B1GAAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8232031-B2 Naphthalenetetracarboxylic acid diimide derivative and electrophotographic photoconductor having the same RICOH COMPANY, LTD. (JP) 2012-07-31 US disclosed
US-8173343-B2 Electrophotographic photoconductor, image forming apparatus using the same, and process cartridge RICOH COMPANY, LTD. (JP) 2012-05-08 US disclosed
EP-2146251-B1 Electrophotographic photoconductor, image forming apparatus using the same, and process cartridge RICOH CO LTD (JP) 2012-02-08 EP disclosed
EP-2033961-B1 Naphthalenetetracarboxylic acid diimide derivative and electrophotographic photoconductor having the same RICOH CO LTD (JP) 2011-03-23 EP disclosed
US-20100015538-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, IMAGE FORMING APPARATUS USING THE SAME, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2010-01-21 US disclosed
EP-2146251-A1 Electrophotographic photoconductor, image forming apparatus using the same, and process cartridge Ricoh Company, Ltd. (JP) 2010-01-20 EP disclosed
US-20090068577-A1 NAPHTHALENETETRACARBOXYLIC ACID DIIMIDE DERIVATIVE AND ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR HAVING THE SAME RICOH COMPANY, LTD. (JP) 2009-03-12 US disclosed
EP-2033961-A1 Naphthalenetetracarboxylic acid diimide derivative and electrophotographic photoconductor having the same Ricoh Company, Ltd. (JP) 2009-03-11 EP disclosed
US-7139512-B2 Charging device, process cartridge and image forming apparatus RICOH COMPANY, LTD. (JP) 2006-11-21 US disclosed
US-20060062598-A1 Charging device, process cartridge and image forming apparatus NAMIKI AKIYO 2006-03-23 US disclosed
US-20030175046-A1 Charging device, process cartridge and image forming apparatus RICOH COMPANY, LTD. (JP) 2003-09-18 US disclosed
US-5439773-A Electrically-conductive toner, process for preparation of same, and process for formation of image using same FUJI XEROX CO., LTD. (JP) 1995-08-08 US disclosed
US-5407770-A Capsule toner and process for producing the same FUJI XEROX CO., LTD. (JP) 1995-04-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090068577-A1 NAPHTHALENETETRACARBOXYLIC ACID DIIMIDE DERIVATIVE AND ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR HAVING THE SAME PAH, AHR, DECR1 KDM4E 922/4885ALDH1A1 207/4885HSD11B1 596/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.