Sugi Predict

Sugi Predict / Compounds / SCHEMBL539276

SCHEMBL539276

SCHEMBL539276

O=C1c2cc(O)ccc2-c2ccc(O)cc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ESR2 Q92731 10/20 0.90
▸ ESR1 P03372 9/20 0.90
▸ MAOA P21397 1/20 0.90
▸ UGT1A1 P22309 1/20 0.90
▸ MAOB P27338 1/20 0.90
▸ TTR P02766 1/20 0.61
▸ MEN1 O00255 1/20 0.56
▸ NPC1 O15118 1/20 0.56
▸ ALDH1A1 P00352 1/20 0.56
▸ GAA P10253 1/20 0.56
▸ MAPT P10636 1/20 0.56
▸ RAB9A P51151 1/20 0.56
▸ KMT2A Q03164 1/20 0.56
▸ L3MBTL1 Q9Y468 1/20 0.56
▸ CA1 P00915 1/20 0.54
▸ CA2 P00918 1/20 0.54
▸ CA7 P43166 1/20 0.54
▸ CA9 Q16790 1/20 0.54
▸ BCL2 P10415 2/20 0.52
▸ MCL1 Q07820 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29486239 1.00 ESR2 (0.90) ESR2ESR1MAOAUGT1A1MAOB
SCHEMBL25270871 0.95 ESR2 (0.90) ESR2ESR1MAOAUGT1A1MAOB
Anthraflavicacid SCHEMBL29985684 0.94 ESR2 (1.00) ESR2ESR1MAOAUGT1A1MAOB
SCHEMBL2772476 0.94 ESR2 (1.00) ESR2ESR1MAOAUGT1A1MAOB
Anthraflavicacid SCHEMBL31105422 0.94 ESR2 (1.00) ESR2ESR1MAOAUGT1A1MAOB
Anthraflavicacid SCHEMBL124974 0.94 ESR2 (1.00) ESR2ESR1MAOAUGT1A1MAOB
SCHEMBL23111390 0.94 ESR2 (0.80) ESR2ESR1MAOAUGT1A1MAOB
Anthraflavicacid SCHEMBL28758924 0.92 ESR2 (0.95) ESR2ESR1MAOAUGT1A1MAOB
SCHEMBL143100 0.91 ESR1 (0.82) ESR2ESR1MAOAUGT1A1MAOB
SCHEMBL31253345 0.91 ESR2 (0.74) ESR2ESR1MAOAUGT1A1MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 292 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12486393-B2 Composition for fluorine rubber crosslinking and molded article DAIKIN INDUSTRIES, LTD. (JP) 2025-12-02 — — US claimed
US-20240409495-A1 PROCESS FOR THE PREPARATION OF 2,7-DIHYDROXY-9-FLUORENONE USEFUL FOR THE SYNTHESIS OF TILORONE AND ITS SALTS COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2024-12-12 — — US claimed
CN-115519842-B Soft sleep-aiding quilt cover fabric and preparation method thereof 江苏斯得福纺织股份有限公司 2024-10-22 — — CN claimed
CN-118290302-A Fluoride ion color developing agent and application thereof in fluoride ion colorimetric detection 常熟三爱富振氟新材料有限公司 2024-07-05 — — CN claimed
CN-118175999-A Process for the preparation of 2, 7-dihydroxy-9-fluorenone useful for the synthesis of telulone and its salts 科学与工业研究委员会 2024-06-11 — — CN claimed
CN-117866013-A Flame-retardant fluorenyl bismaleimide resin and preparation method thereof 四川泸天化创新研究院有限公司 2024-04-12 — — CN claimed
CN-117362644-A Polyimide resin for improving hydrophobicity of cotton fabric and preparation method thereof 韶关市北纺智造科技有限公司 2024-01-09 — — CN claimed
CN-115028522-B Preparation method of 2, 7-dihydroxy-9-fluorenone 杭州卢普生物科技有限公司 2023-10-24 — — CN claimed
CN-116573989-A Preparation method of tetraphenol fluorene and preparation method of tetraphenol fluorenyl epoxy resin 湖南大学 2023-08-11 — — CN claimed
EP-4215576-A1 COMPOSITION FOR FLUORINE RUBBER CROSSLINKING AND MOLDED ARTICLE Daikin Industries, Ltd. (JP) 2023-07-26 — — EP claimed
CN-103936765-A N-full aromatic hydrocarbyl bisphenol-diamine tetrafunctional fluorene-based benzoxazine and preparation method thereof UNIV HARBIN ENG 2014-07-23 — — CN claimed
US-8748664-B2 Diamine compound and production method thereof NITTO DENKO CORPORATION (JP) 2014-06-10 — — US claimed
EP-2692721-A1 DIAMINE COMPOUND CONTAINING SULFONIC ACID GROUP, AND METHOD FOR PRODUCING SAME Nitto Denko Corporation (JP) 2014-02-05 — — EP claimed
CN-103204781-A 2, 7-bi-substituted fluorenone derivative and preparation method and application thereof UNIV WUHAN 2013-07-17 — — CN claimed
US-20130178649-A1 SULFONIC ACID GROUP-CONTAINING DIAMINE COMPOUND AND METHOD FOR PRODUCING THE SAME NITTO DENKO CORPORATION (JP) 2013-07-11 — — US claimed
CN-103193755-A Spirofluorene xanthene phenol compound and preparation method thereof UNIV HARBIN ENG 2013-07-10 — — CN claimed
CN-103145730-A Bithienofluorene, its derivative and preparation method UNIV EAST CHINA NORMAL 2013-06-12 — — CN claimed
US-20130006017-A1 NOVEL DIAMINE COMPOUND AND PRODUCTION METHOD THEREOF NITTO DENKO CORPORATION (JP) 2013-01-03 — — US claimed
EP-2540699-A1 NOVEL DIAMINE COMPOUND AND PRODUCTION METHOD THEREOF Nitto Denko Corporation (JP) 2013-01-02 — — EP claimed
CN-102659526-A Tetraphenolic hydroxyfluorene compound and preparation method thereof UNIV HARBIN ENG 2012-09-12 — — CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130178649-A1 SULFONIC ACID GROUP-CONTAINING DIAMINE COMPOUND AND METHOD FOR PRODUCING THE SAME SAT1, DAO, SRM ESR2 3146/4885ESR1 2842/4885MAOA 498/4885
US-20130006017-A1 NOVEL DIAMINE COMPOUND AND PRODUCTION METHOD THEREOF AOC1, SAT1, ODC1 ESR2 2717/4885ESR1 2747/4885MAOA 251/4885
US-20240409495-A1 PROCESS FOR THE PREPARATION OF 2,7-DIHYDROXY-9-FLUORENONE USEFUL FOR THE SYNTHESIS OF TILORONE AND ITS SALTS TALDO1, TKFC, DHCR7 ESR2 2383/4885ESR1 2216/4885MAOA 1272/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.