Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 10/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5334028 | 0.91 | HTR4 (0.57) | HTR4CYP3A4ACHE | |
| SCHEMBL5341243 | 0.91 | HTR4 (0.60) | HTR4CYP3A4ACHE | |
| SCHEMBL5344593 | 0.90 | HTR4 (0.62) | HTR4CYP3A4ACHE | |
| SCHEMBL5116451 | 0.89 | HTR4 (0.64) | HTR4CYP3A4ACHE | |
| SCHEMBL5120793 | 0.87 | HTR4 (0.64) | HTR4CYP3A4ACHE | |
| SCHEMBL5121617 | 0.86 | HTR4 (0.63) | HTR4CYP3A4ACHE | |
| SCHEMBL5127825 | 0.86 | HTR4 (0.63) | HTR4CYP3A4ACHE | |
| SCHEMBL5346572 | 0.84 | HTR4 (0.62) | HTR4CYP3A4ACHE | |
| SCHEMBL5349482 | 0.84 | HTR4 (0.53) | HTR4CYP3A4ACHE | |
| SCHEMBL5124075 | 0.83 | HTR4 (0.64) | HTR4CYP3A4ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1856114-A1 | BENZISOXAZOLE DERIVATIVES | Pfizer, Inc. (US) | 2007-11-21 | — | — | EP | disclosed |
| WO-2006090224-A1 | BENZISOXAZOLE DERIVATIVES | PFIZER JAPAN INC. (JP) | 2006-08-31 | — | — | WO | disclosed |