⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3362075 | 0.80 | — | — | |
| SCHEMBL5083 | 0.79 | — | — | |
| SCHEMBL1679282 | 0.78 | TAAR1 (0.64) | — | |
| SCHEMBL285224 | 0.78 | TERT (0.59) | — | |
| SCHEMBL7720717 | 0.77 | — | — | |
| SCHEMBL7300422 | 0.76 | — | — | |
| SCHEMBL3030816 | 0.75 | TBXAS1 (0.56) | — | |
| SCHEMBL1372542 | 0.74 | — | — | |
| SCHEMBL633945 | 0.74 | — | — | |
| SCHEMBL9675957 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 271 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4140991-B1 | INHIBITORS OF OPLOPHORUS LUCIFERASE-DERIVED BIOLUMINESCENT COMPLEXES | PROMEGA CORP (US) | 2024-05-15 | — | — | EP | disclosed |
| EP-3861001-B1 | BORON CONTAINING PDE4 INHIBITORS | PFIZER (US) | 2023-12-13 | — | — | EP | disclosed |
| US-20230338344-A1 | AMPK Activators and Methods of Use Thereof | BIOVERATIV THERAPEUTICS INC. (US) | 2023-10-26 | — | — | US | disclosed |
| EP-4221700-A1 | AMPK ACTIVATORS AND METHODS OF USE THEREOF | Bioverativ Therapeutics Inc. (US) | 2023-08-09 | — | — | EP | disclosed |
| US-20230148402-A1 | Boron Containing PDE4 Inhibitors | PFIZER INC. (US) | 2023-05-11 | — | — | US | disclosed |
| EP-4140991-A1 | INHIBITORS OF OPLOPHORUS LUCIFERASE-DERIVED BIOLUMINESCENT COMPLEXES | Promega Corporation (US) | 2023-03-01 | — | — | EP | disclosed |
| EP-3562823-B1 | FUNCTIONALIZED NANOLUC INHIBITORS | PROMEGA CORP (US) | 2023-02-08 | — | — | EP | disclosed |
| US-11559538-B2 | Substituted 1,2-oxaborolan-2-ols as PDE4 inhibitors | PFIZER INC. (US) | 2023-01-24 | — | — | US | disclosed |
| US-20220291223-A1 | CHEMILUMINESCENT COMPOUNDS FOR MULTIPLEXING | ABBOTT LAB (US) | 2022-09-15 | — | — | US | disclosed |
| US-11390599-B2 | Inhibitors of oplophorus luciferase-derived bioluminescent complexes | PROMEGA CORPORATION (US) | 2022-07-19 | — | — | US | disclosed |
| US-5492947-A | Barrier material comprising a thermoplastic and a compatible cyclodextrin derivative | ASPEN RESEARCH CORPORATION (US) | 1996-02-20 | — | — | US | disclosed |
| WO-1996000260-A1 | A BARRIER MATERIAL COMPRISING A THERMOPLASTIC AND A COMPATIBLE CYCLODEXTRIN DERIVATIVE | ASPEN RESEARCH CORPORATION (US) | 1996-01-04 | — | — | WO | disclosed |
| EP-0139614-B1 | PHARMACEUTICAL PREPARATIONS CONTAINING FLAVANONE OR THIOFLAVANONE DERIVATIVES, THE USE THEREOF, NOVEL FLAVANONES AND THIOFLAVANONES, AND PROCESSES FOR THEIR MANUFACTURE | Zyma SA (CH) | 1990-08-22 | — | — | EP | disclosed |
| US-4935441-A | Flavene and thioflavene derivates, processes for their manufacture, pharmaceutical preparations that contain such compounds, and the use of the latter | ZYMA SA (CH) | 1990-06-19 | — | — | US | disclosed |
| US-4885298-A | Pharmaceutical preparations containing flavanone or thioflavanone derivatives the use thereof, novel flavanones and thioflavanones, and processes for their manufacture | ZYMA SA (CH) | 1989-12-05 | — | — | US | disclosed |
| EP-0140830-B1 | PHARMACEUTICAL PREPARATIONS CONTAINING FLAVENE OR THIOFLAVENE DERIVATIVES, THE USE THEREOF, NOVEL FLAVENES AND THIOFLAVENES, AND PROCESSES FOR THEIR MANUFACTURE | Zyma SA (CH) | 1989-08-30 | — | — | EP | disclosed |
| US-4665202-A | Flavene and thioflavene derivatives | ZYMA SA (CH) | 1987-05-12 | — | — | US | disclosed |
| EP-0140830-A2 | Pharmaceutical preparations containing flavene or thioflavene derivatives, the use thereof, novel flavenes and thioflavenes, and processes for their manufacture | Zyma SA (CH) | 1985-05-08 | — | — | EP | disclosed |
| EP-0139615-A2 | Flavene and thioflavene derivatives, processes for their manufacture, pharmaceutical preparations that contain such compounds, and the use of the latter | Zyma SA (CH) | 1985-05-02 | — | — | EP | disclosed |
| EP-0139614-A2 | Pharmaceutical preparations containing flavanone or thioflavanone derivatives, the use thereof, novel flavanones and thioflavanones, and processes for their manufacture | Zyma SA (CH) | 1985-05-02 | — | — | EP | disclosed |