⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL181657 | 0.80 | — | — | |
| SCHEMBL53958 | 0.79 | — | — | |
| SCHEMBL285224 | 0.78 | TERT (0.59) | — | |
| SCHEMBL1679282 | 0.78 | TAAR1 (0.64) | — | |
| SCHEMBL8052261 | 0.77 | ALOX15 (0.48) | — | |
| SCHEMBL181705 | 0.77 | — | — | |
| SCHEMBL7300422 | 0.76 | — | — | |
| SCHEMBL28116124 | 0.75 | — | — | |
| SCHEMBL181392 | 0.75 | TBXAS1 (0.56) | — | |
| SCHEMBL53959 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3667 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11999739-B2 | Antimicrobials methods of making and using the same | BioVersys AG (CH) | 2024-06-04 | — | — | US | claimed |
| WO-2024022481-A1 | PHENYL-SUBSTITUTED DIHYDRONAPHTHYRIDINE COMPOUNDS, AND PREPARATION AND USE THEREOF | 苏中药业集团股份有限公司 | 2024-02-01 | — | — | WO | claimed |
| WO-2023217764-A1 | NOX INHIBITORS FOR USE IN THE TREATMENT OF ALPORT SYNDROME | CALLIDITAS THERAPEUTICS SUISSE SA (CH) | 2023-11-16 | — | — | WO | claimed |
| EP-3480187-B1 | METHOD FOR PREPARING INDENOISOQUINOLINE DERIVATIVES | UNIV NAT TAIWAN NORMAL (TW) | 2023-10-04 | — | — | EP | claimed |
| EP-4217358-A1 | INDAZOLES AS HEMATOPOIETIC PROGENITOR KINASE 1 (HPK1) INHIBITORS AND METHODS OF USING SAME | 1st Biotherapeutics, Inc. (KR) | 2023-08-02 | — | — | EP | claimed |
| US-20230192631-A1 | Biphenyl Derivatives | HOFFMANN-LA ROCHE INC. (US) | 2023-06-22 | — | — | US | claimed |
| US-11649255-B2 | Indazoles as hematopoietic progenitor kinase 1 (HPK1) inhibitors and methods using same | 1ST Biotherapeutics, Inc. (KR) | 2023-05-16 | — | — | US | claimed |
| EP-4136076-A1 | BIPHENYL DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2023-02-22 | — | — | EP | claimed |
| CN-115397813-A | Biphenyl derivatives | 豪夫迈·罗氏有限公司 | 2022-11-25 | — | — | CN | claimed |
| CN-114599653-A | Indazoles as inhibitors of hematopoietic progenitor kinase 1(HPK1) and methods of use thereof | 第一生物治疗股份有限公司 | 2022-06-07 | — | — | CN | claimed |
| EP-0349922-A2 | Aminoalkylaminocarbonyl aminodiol amino acid derivatives as anti-hypertensive agents | G.D. Searle & Co. (US) | 1990-01-10 | — | — | EP | claimed |
| EP-0349921-A2 | Etheral n-terminal aminodiol amino acid derivatives as anti-hypertensive agents | G.D. Searle & Co. (US) | 1990-01-10 | — | — | EP | claimed |
| US-4695630-A | Cycloacetals | BAYER AKTIENGESELLSCHAFT (DE) | 1987-09-22 | — | — | US | claimed |
| EP-0233015-A2 | 1,4-Dihydropyridines | JOHN WYETH & BROTHER LIMITED (GB) | 1987-08-19 | — | — | EP | claimed |
| EP-0220865-A2 | Lactam derivatives, their preparation and their use as hypotensive agents | SANKYO COMPANY LIMITED (JP) | 1987-05-06 | — | — | EP | claimed |
| CN-85106495-A | The method for preparing heterogeneous ring compound | — | 1987-02-11 | — | — | CN | claimed |
| EP-0172029-A1 | 1,4-Dihydropyridines | JOHN WYETH & BROTHER LIMITED (GB) | 1986-02-19 | — | — | EP | claimed |
| EP-0132101-A1 | 2-Heterocycloalkylthiopenem derivatives | PFIZER INC. (US) | 1985-01-23 | — | — | EP | claimed |
| US-4192879-A | HISTAMINE H2-ANTAGONISTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1980-03-11 | — | — | US | claimed |
| US-4166856-A | Thiazole and isothiazole derivative as blockers of histamine H2 -receptors | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1979-09-04 | — | — | US | claimed |