Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.48 |
| ▸ | NOS1 | P29475 | 1/20 | 0.48 |
| ▸ | NOS2 | P35228 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 5/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | GABRP | O00591 | 1/20 | 0.44 |
| ▸ | GABRD | O14764 | 1/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.44 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.44 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.44 |
| ▸ | GABRE | P78334 | 1/20 | 0.44 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30875970 | 1.00 | NOS3 (0.48) | NOS3NOS1NOS2ALDH1A1MAPT | |
| SCHEMBL7006193 | 0.88 | CTSB (0.43) | NOS3NOS1NOS2ALDH1A1MAPT | |
| SCHEMBL29392605 | 0.80 | MERTK (0.51) | MAPTTSHRCYP3A4TDP1HSD17B10 | |
| SCHEMBL11198744 | 0.80 | MAPT (0.45) | ALDH1A1MAPTTSHRCYP3A4TDP1 | |
| SCHEMBL381701 | 0.80 | MERTK (0.51) | MAPTTSHRCYP3A4TDP1HSD17B10 | |
| SCHEMBL671296 | 0.79 | TDP1 (0.45) | ALDH1A1MAPTTSHRCYP3A4RECQL | |
| SCHEMBL29391396 | 0.79 | TDP1 (0.45) | ALDH1A1MAPTTSHRCYP3A4RECQL | |
| SCHEMBL1135629 | 0.79 | CTSB (0.54) | ALDH1A1MAPTTSHRCYP3A4TDP1 | |
| SCHEMBL30810188 | 0.79 | CTSB (0.54) | ALDH1A1MAPTTSHRCYP3A4TDP1 | |
| SCHEMBL27809340 | 0.77 | TSHR (0.41) | ALDH1A1MAPTTSHRCYP3A4RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 186 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102775404-B | Method for synthesizing 5-chloro-4-azaindole | CHEMFUTURE PHARMATECH JIANGSU LTD | 2015-06-03 | — | — | CN | claimed |
| CN-102775404-A | Method for synthesizing 5-chloro-4-azaindole | CHEMFUTURE PHARMATECH JIANGSU LTD | 2012-11-14 | — | — | CN | claimed |
| EP-0916669-B1 | Processes and intermediates for the preparation of Pyrrolo(3,2-b)pyridine | LILLY CO ELI (US) | 2003-04-09 | — | — | EP | claimed |
| CN-1278814-A | Pyrrolo [3,2-b] pyridine processes and intermediates | LILLY CO ELI (US) | 2001-01-03 | — | — | CN | claimed |
| US-6150525-A | Pyrrolo [3,2-b]pyridine processes and intermediates | ELI LILLY AND COMPANY (US) | 2000-11-21 | — | — | US | claimed |
| WO-1999025708-A1 | PYRROLO[3,2-b]PYRIDINE PROCESSES AND INTERMEDIATES | ELI LILLY AND COMPANY (US) | 1999-05-27 | — | — | WO | claimed |
| EP-0916669-A2 | Processes and intermediates for the preparation of Pyrrolo(3,2-b)pyridine | ELI LILLY AND COMPANY (US) | 1999-05-19 | — | — | EP | claimed |
| EP-4687881-A2 | HETEROARYL ANTIDEGRADANTS | Flexsys IP Holdings, LLC (US) | 2026-02-11 | — | — | EP | disclosed |
| WO-2025059577-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS FOR USE AS AKT1 INHIBITORS | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |
| CN-115572285-B | OCT4 high-selectivity activator | 武汉睿健医药科技有限公司 | 2024-10-29 | — | — | CN | disclosed |
| WO-2024206786-A2 | HETEROARYL ANTIDEGRADANTS | FLEXSYS AMERICA L.P. (US) | 2024-10-03 | — | — | WO | disclosed |
| WO-2024001967-A1 | IMIDAZONAPHTHYRIDINE COMPOUND WITH AFFINITY WITH TAU PROTEIN, METHOD FOR PREPARING SAME, AND USE THEREOF | 北京师范大学 | 2024-01-04 | — | — | WO | disclosed |
| CN-115322197-B | Imidazonaphthyridine compound with affinity with Tau protein, and preparation method and application thereof | 北京师范大学 | 2023-09-29 | — | — | CN | disclosed |
| EP-0399731-B1 | Azaindenes | ZENECA LTD (GB) | 1993-12-08 | — | — | EP | disclosed |
| WO-1993023399-A1 | 6-AMINO SUBSTITUTED IMIDAZO[4,5-b]PYRIDINES AS ANGIOTENSIN II ANTAGONISTS | MERCK & CO., INC. (US) | 1993-11-25 | — | — | WO | disclosed |
| US-5223499-A | Hypotensive agents | MERCK & CO., INC. (US) | 1993-06-29 | — | — | US | disclosed |
| EP-0399731-A1 | Azaindenes | ZENECA LIMITED (GB) | 1990-11-28 | — | — | EP | disclosed |
| EP-0137524-B1 | HAIR DYEING COMPOSITIONS | RÜTGERSWERKE AKTIENGESELLSCHAFT (DE) | 1988-01-20 | — | — | EP | disclosed |
| US-4647569-A | Antiarthritic pyridylaminoethene disulfonyl compounds and use | MAY & BAKER LIMITED (GB) | 1987-03-03 | — | — | US | disclosed |
| EP-0137524-A1 | Hair dyeing compositions | RÜTGERSWERKE AKTIENGESELLSCHAFT (DE) | 1985-04-17 | — | — | EP | disclosed |