Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MERTK | Q12866 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | TXNRD1 | Q16881 | 4/20 | 0.47 |
| ▸ | GSR | P00390 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | CTSH | P09668 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL381701 | 1.00 | MERTK (0.51) | MERTKMAPTTXNRD1GSRTDP1 | |
| SCHEMBL56616 | 0.83 | MAPT (0.50) | MERTKMAPTTXNRD1GSRTDP1 | |
| SCHEMBL29364858 | 0.83 | MAPT (0.50) | MERTKMAPTTXNRD1GSRTDP1 | |
| SCHEMBL5971901 | 0.80 | ALDH1A1 (0.61) | MERTKMAPTTXNRD1GSRTDP1 | |
| SCHEMBL30875970 | 0.80 | NOS3 (0.48) | MAPTTDP1L3MBTL1POLBTSHR | |
| SCHEMBL539616 | 0.80 | NOS3 (0.48) | MAPTTDP1L3MBTL1POLBTSHR | |
| SCHEMBL1128565 | 0.80 | TSHR (0.44) | MERTKMAPTTXNRD1TDP1L3MBTL1 | |
| SCHEMBL30810188 | 0.79 | CTSB (0.54) | MAPTTDP1L3MBTL1POLBTSHR | |
| SCHEMBL1135629 | 0.79 | CTSB (0.54) | MAPTTDP1L3MBTL1POLBTSHR | |
| SCHEMBL136263 | 0.78 | CTSB (0.53) | MERTKMAPTTDP1L3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025215153-A1 | PRMT5 INHIBITORS | Ryvu Therapeutics S.A. (PL) | 2025-10-16 | — | — | WO | disclosed |
| EP-3953335-A1 | INHIBITORS OF NOTCH SIGNALLING PATHWAY AND USE THEREOF IN TREATMENT OF CANCERS | Cellestia Biotech AG (CH) | 2022-02-16 | — | — | EP | disclosed |