Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | ATM | Q13315 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 2/20 | 0.36 |
| ▸ | FAP | Q12884 | 2/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.35 |
| ▸ | PTGES | O14684 | 1/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CETP | P11597 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28314023 | 0.92 | TDP1 (0.43) | TDP1ATMLMNAADRA2ACNR1 | |
| SCHEMBL8680251 | 0.91 | TDP1 (0.41) | TDP1ATMLMNAADRA2ACNR1 | |
| SCHEMBL5043710 | 0.86 | TDP1 (0.54) | TDP1ATMLMNAADRA2ACNR1 | |
| SCHEMBL9020889 | 0.86 | TDP1 (0.54) | TDP1ATMLMNAADRA2ACNR1 | |
| SCHEMBL8210825 | 0.86 | TDP1 (0.54) | TDP1ATMLMNAADRA2ACNR1 | |
| SCHEMBL11200747 | 0.84 | TDP1 (0.47) | TDP1ATMLMNAADRA2ACNR1 | |
| SCHEMBL11220475 | 0.81 | TDP1 (0.48) | TDP1ATMLMNAADRA2ACNR1 | |
| SCHEMBL11152897 | 0.79 | TDP1 (0.46) | TDP1ATMLMNAADRA2ACNR1 | |
| SCHEMBL23824720 | 0.78 | TDP1 (0.54) | TDP1ATMLMNAADRA2ACNR1 | |
| SCHEMBL5854396 | 0.78 | TDP1 (0.54) | TDP1ATMLMNAADRA2ACNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7215878-B2 | Chip that comprises an active agent and an integrated heating element | S.C. JOHNSON & SON, INC. (US) | 2007-05-08 | — | — | US | disclosed |
| US-20030049025-A1 | Chip that comprises an active agent and an integrated heating element | S.C. JOHNSON & SON, INC. | 2003-03-13 | — | — | US | disclosed |