Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 10/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.35 |
| ▸ | PTGES | O14684 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | GNA15 | P30679 | 1/20 | 0.34 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5397496 | 0.91 | TDP1 (0.48) | TDP1ATMLMNAADRA2ACNR1 | |
| SCHEMBL28314023 | 0.87 | TDP1 (0.43) | TDP1ATMLMNAADRA2ACNR1 | |
| SCHEMBL11592061 | 0.87 | TDP1 (0.46) | TDP1ATMLMNAADRA2ACNR1 | |
| SCHEMBL10829249 | 0.87 | TDP1 (0.46) | TDP1ATMLMNAADRA2ACNR1 | |
| SCHEMBL8304055 | 0.87 | TDP1 (0.46) | TDP1ATMLMNAADRA2ACNR1 | |
| SCHEMBL10940398 | 0.80 | TDP1 (0.41) | TDP1ATMLMNAADRA2ACNR1 | |
| SCHEMBL23824720 | 0.77 | TDP1 (0.54) | TDP1ATMLMNAADRA2ACNR1 | |
| SCHEMBL8210825 | 0.77 | TDP1 (0.54) | TDP1ATMLMNAADRA2ACNR1 | |
| SCHEMBL5854396 | 0.77 | TDP1 (0.54) | TDP1ATMLMNAADRA2ACNR1 | |
| SCHEMBL5043710 | 0.77 | TDP1 (0.54) | TDP1ATMLMNAADRA2ACNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998016487-A1 | 1S TO 1R EPIMERIZATIONS OF PYRETHROID INTERMEDIATES | FMC CORPORATION (US) | 1998-04-23 | — | — | WO | disclosed |