Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | NLRP3 | Q96P20 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.37 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.37 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.37 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7557601 | 0.90 | ALDH1A1 (0.42) | ALDH1A1NLRP3KMT2AKCNQ3KCNQ2 | |
| SCHEMBL7563124 | 0.85 | ALDH1A1 (0.40) | ALDH1A1NLRP3KMT2AKCNQ3KCNQ2 | |
| SCHEMBL7664551 | 0.84 | ALDH1A1 (0.45) | ALDH1A1NLRP3KMT2ACYP1A2CYP2C9 | |
| SCHEMBL7557293 | 0.79 | ALDH1A1 (0.48) | ALDH1A1NLRP3KMT2ACYP1A2CYP2C9 | |
| SCHEMBL31569139 | 0.76 | SMN1; SMN2 (0.48) | ALDH1A1KMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7558526 | 0.75 | NLRP3 (0.54) | ALDH1A1NLRP3KMT2AKCNQ3KCNQ2 | |
| SCHEMBL7562049 | 0.75 | KCNQ3 (0.45) | ALDH1A1NLRP3KMT2AKCNQ3KCNQ2 | |
| SCHEMBL5385415 | 0.72 | POLB (0.44) | ALDH1A1KMT2ACYP1A2SMN1; SMN2KDM4E | |
| SCHEMBL28910196 | 0.72 | MAPT (0.42) | ALDH1A1KMT2ASMN1; SMN2KDM4EMAPT | |
| SCHEMBL11046716 | 0.71 | NLRP3 (0.44) | ALDH1A1NLRP3KMT2ACYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE39590-E1 | Substituted benzene compounds, process for their preparation, and herbicidal and defoliant compositions containing them | ISK AMERICAS INCORPORATED (US) | 2007-04-24 | — | — | US | disclosed |
| US-6545161-B2 | Potato and corn crops | ISK AMERICAS INCORPORATED | 2003-04-08 | — | — | US | disclosed |
| EP-1030843-A4 | SUBSTITUTED BENZENE COMPOUNDS, PROCESS FOR THEIR PREPARATION, AND HERBICIDAL AND DEFOLIANT COMPOSITIONS CONTAINING THEM | ISK AMERICAS INC (US) | 2002-11-06 | — | — | EP | disclosed |
| US-20020133007-A1 | Substituted benzene compounds, process for their preparation, and herbicidal and defoliant compositions containing them | ISK AMERICAS INCORPORATED | 2002-09-19 | — | — | US | disclosed |
| US-6355799-B1 | PREEMERGENT HERBICIDE FOR CEREAL CROP FIELDS, DEFOLIANT FOR POTATO AND COTTON PLANTS | ISK AMERICAS INCORPORATED | 2002-03-12 | — | — | US | disclosed |
| EP-1030843-A1 | SUBSTITUTED BENZENE COMPOUNDS, PROCESS FOR THEIR PREPARATION, AND HERBICIDAL AND DEFOLIANT COMPOSITIONS CONTAINING THEM | ISK Americas Incorporated (US) | 2000-08-30 | — | — | EP | disclosed |
| WO-1999021837-A1 | SUBSTITUTED BENZENE COMPOUNDS, PROCESS FOR THEIR PREPARATION, AND HERBICIDAL AND DEFOLIANT COMPOSITIONS CONTAINING THEM | ISK AMERICAS INCORPORATED (US) | 1999-05-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020133007-A1 | Substituted benzene compounds, process for their preparation, and herbicidal and defoliant compositions containing them | DDT, CYP4X1, CYP1A1 | ALDH1A1 753/4885NLRP3 1159/4885KMT2A 2175/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.