Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GALR2 | O43603 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | CCR6 | P51684 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7558526 | 0.85 | NLRP3 (0.54) | ALDH1A1SMN1; SMN2POLBNLRP3KMT2A | |
| SCHEMBL7554735 | 0.79 | NLRP3 (0.45) | ALDH1A1SMN1; SMN2POLBNLRP3KMT2A | |
| SCHEMBL5397703 | 0.79 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2HPGDPOLBLMNA | |
| SCHEMBL7557601 | 0.79 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2HPGDPOLBLMNA | |
| SCHEMBL7563124 | 0.77 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2NLRP3MAPTKMT2A | |
| SCHEMBL15357242 | 0.76 | KCNQ3 (0.57) | ALDH1A1SMN1; SMN2HPGDPOLBLMNA | |
| SCHEMBL7664551 | 0.76 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2NLRP3PKMKMT2A | |
| SCHEMBL15415300 | 0.75 | GAA (0.38) | ALDH1A1SMN1; SMN2HPGDLMNAMAPT | |
| SCHEMBL8700206 | 0.75 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2HPGDPOLBLMNA | |
| SCHEMBL7013091 | 0.75 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2HPGDPOLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002056681-A2 | NOVEL INTERMEDIATES AND PROCESS TO PYRIMIDINEDIONE HERBICIDES | FMC CORPORATION (US) | 2002-07-25 | — | — | WO | disclosed |