Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMP1 | P13497 | 20/20 | 0.64 |
| ▸ | MMP1 | P03956 | 1/20 | 0.49 |
| ▸ | MMP3 | P08254 | 1/20 | 0.49 |
| ▸ | MMP13 | P45452 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5408338 | 0.94 | BMP1 (0.72) | BMP1MMP1MMP3MMP13 | |
| SCHEMBL5408485 | 0.91 | BMP1 (0.73) | BMP1MMP1MMP3MMP13 | |
| SCHEMBL5405119 | 0.91 | BMP1 (0.73) | BMP1MMP1MMP3MMP13 | |
| SCHEMBL5759837 | 0.88 | BMP1 (0.69) | BMP1MMP1MMP3MMP13 | |
| SCHEMBL5404121 | 0.87 | BMP1 (0.61) | BMP1MMP1MMP3MMP13 | |
| SCHEMBL5410998 | 0.86 | BMP1 (0.86) | BMP1MMP1MMP3MMP13 | |
| SCHEMBL27567368 | 0.85 | BMP1 (0.59) | BMP1MMP1MMP3MMP13 | |
| SCHEMBL5406814 | 0.85 | BMP1 (0.59) | BMP1MMP1MMP3MMP13 | |
| SCHEMBL5409852 | 0.85 | BMP1 (0.70) | BMP1MMP1MMP3MMP13 | |
| Trifluoroacetic Acid SCHEMBL5404116 | 0.84 | BMP1 (0.64) | BMP1MMP1MMP3MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7214694-B2 | 3-ox(adi)azolylpropanohydroxamic acids useful as procollagen C-proteinase inhibitors | PFIZER INC (US) | 2007-05-08 | — | — | US | disclosed |
| US-7214694-B2 | 3-ox(adi)azolylpropanohydroxamic acids useful as procollagen C-proteinase inhibitors | PFIZER INC (US) | 2007-05-08 | — | — | US | disclosed |
| US-7214694-B2 | 3-ox(adi)azolylpropanohydroxamic acids useful as procollagen C-proteinase inhibitors | PFIZER INC (US) | 2007-05-08 | — | — | US | disclosed |
| US-20040142986-A1 | 3-ox(adi)azolylpropanohydroxamic acids useful as procollagen C-proteinase inhibitors | DATTA USA (GB) | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142986-A1 | 3-ox(adi)azolylpropanohydroxamic acids useful as procollagen C-proteinase inhibitors | ALPI, TIMP3, MMP1 | BMP1 376/4885MMP1 3/4885MMP3 9/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.