Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.37 |
| ▸ | CCR8 | P51685 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1474804 | 0.79 | ALDH1A1 (0.41) | KCNH2CCR8ALDH1A1KDM4EPOLB | |
| SCHEMBL12827514 | 0.74 | ALDH1A1 (0.48) | KCNH2CCR8ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL5400844 | 0.74 | DPP4 (0.38) | KCNH2CCR8ALDH1A1KDM4EPOLB | |
| SCHEMBL5400852 | 0.72 | USP7 (0.37) | KCNH2CCR8ALDH1A1KDM4EPOLB | |
| SCHEMBL5400845 | 0.71 | TACR1 (0.42) | KCNH2CCR8ALDH1A1KMT2AMEN1 | |
| SCHEMBL1476057 | 0.70 | CCR8 (0.38) | KCNH2CCR8ALDH1A1KDM4EPOLB | |
| SCHEMBL1476956 | 0.70 | KCNH2 (0.44) | KCNH2CCR8ALDH1A1KDM4EPOLB | |
| SCHEMBL1476401 | 0.69 | TACR2 (0.46) | KCNH2ALDH1A1KDM4EPOLBCYP1A2 | |
| SCHEMBL1475562 | 0.69 | KCNH2 (0.40) | KCNH2CCR8ALDH1A1KDM4EPOLB | |
| SCHEMBL1474461 | 0.69 | KCNH2 (0.40) | KCNH2CCR8ALDH1A1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7265108-B2 | Nitrogen containing heterocyclic compounds and medicines containing the same | EISAI CO., LTD. (JP) | 2007-09-04 | — | — | US | disclosed |