Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 10/20 | 0.42 |
| ▸ | USP7 | Q93009 | 3/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | CCR8 | P51685 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5400852 | 0.90 | USP7 (0.37) | TACR1USP7DRD2DRD4DRD3 | |
| SCHEMBL1474804 | 0.82 | ALDH1A1 (0.41) | USP7DRD2DRD4DRD3CCR8 | |
| SCHEMBL5400844 | 0.79 | DPP4 (0.38) | TACR1USP7DRD2DRD4DRD3 | |
| SCHEMBL1476956 | 0.75 | KCNH2 (0.44) | USP7DRD2DRD4DRD3CCR8 | |
| SCHEMBL12827514 | 0.73 | ALDH1A1 (0.48) | DRD2DRD4DRD3CCR8KCNH2 | |
| SCHEMBL5400840 | 0.71 | KCNH2 (0.37) | CCR8KCNH2MEN1KMT2AGAA | |
| SCHEMBL1475562 | 0.70 | KCNH2 (0.40) | CCR8KCNH2KMT2AGAAALDH1A1 | |
| SCHEMBL1475951 | 0.70 | CCR8 (0.42) | CCR8KCNH2MEN1KMT2AATM | |
| SCHEMBL1476057 | 0.69 | CCR8 (0.38) | USP7DRD2DRD4DRD3CCR8 | |
| SCHEMBL1475312 | 0.68 | KCNH2 (0.43) | CCR8KCNH2KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7265108-B2 | Nitrogen containing heterocyclic compounds and medicines containing the same | EISAI CO., LTD. (JP) | 2007-09-04 | — | — | US | disclosed |