Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | FNTA | P49354 | 4/20 | 0.52 |
| ▸ | FNTB | P49356 | 4/20 | 0.52 |
| ▸ | MMP1 | P03956 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | MMP14 | P50281 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11718612 | 0.89 | FFAR1 (0.54) | ALDH1A1CA2MAPTMEN1GAA | |
| SCHEMBL159434 | 0.89 | FFAR1 (0.54) | ALDH1A1CA2MAPTMEN1GAA | |
| SCHEMBL28847226 | 0.87 | FFAR1 (0.53) | ALDH1A1CA2MAPTKDM4EMEN1 | |
| SCHEMBL10538012 | 0.87 | FFAR1 (0.53) | ALDH1A1CA2MAPTKDM4EMEN1 | |
| SCHEMBL5954356 | 0.86 | FFAR1 (0.59) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL5411982 | 0.80 | POLB (0.62) | ALDH1A1L3MBTL1MAPTKDM4EMEN1 | |
| SCHEMBL8729773 | 0.80 | KMT2A (0.60) | ALDH1A1L3MBTL1MAPTMEN1KMT2A | |
| Dioxane SCHEMBL28200326 | 0.79 | FFAR1 (0.46) | ALDH1A1CA2MAPTKDM4EMEN1 | |
| SCHEMBL11715952 | 0.79 | FFAR1 (0.46) | ALDH1A1CA2MAPTMEN1GAA | |
| SCHEMBL5692310 | 0.79 | ALDH1A1 (0.44) | ALDH1A1CA2MMP2MMP9CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7202269-B2 | GlyT2 modulators | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-04-10 | — | — | US | disclosed |
| US-20050119245-A1 | GlyT2 modulators | JANSSEN PHARMACEUTICA, N.V. (BE) | 2005-06-02 | — | — | US | disclosed |
| WO-2005044810-A1 | GLYT2 MODULATORS | JANSSEN PHARMACEUTICA, N.V. (BE) | 2005-05-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050119245-A1 | GlyT2 modulators | GLRB, GLRA1, GLRA2 | ALDH1A1 3023/4885L3MBTL1 1343/4885FNTA 279/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.