Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PHGDH | O43175 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11718612 | 0.89 | FFAR1 (0.54) | FFAR1MAPTALDH1A1NPC1RAB9A | |
| SCHEMBL159434 | 0.89 | FFAR1 (0.54) | FFAR1MAPTALDH1A1NPC1RAB9A | |
| SCHEMBL10538012 | 0.87 | FFAR1 (0.53) | FFAR1MAPTALDH1A1NPC1RAB9A | |
| SCHEMBL28847226 | 0.87 | FFAR1 (0.53) | FFAR1MAPTALDH1A1NPC1RAB9A | |
| Dioxane SCHEMBL28200327 | 0.84 | ALDH1A1 (0.49) | FFAR1SMN1; SMN2MAPTALDH1A1RAB9A | |
| SCHEMBL11715952 | 0.79 | FFAR1 (0.46) | FFAR1MAPTALDH1A1MEN1LMNA | |
| SCHEMBL5400908 | 0.79 | ALDH1A1 (0.57) | FFAR1SMN1; SMN2MAPTALDH1A1MEN1 | |
| SCHEMBL5692310 | 0.79 | ALDH1A1 (0.44) | FFAR1SMN1; SMN2MAPTALDH1A1NPC1 | |
| SCHEMBL7851509 | 0.77 | MEN1 (0.50) | FFAR1MAPTCNR1ALDH1A1NPC1 | |
| SCHEMBL6625019 | 0.77 | L3MBTL1 (0.58) | SMN1; SMN2MAPTALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105418516-B | A kind of quinazoline compounds and preparation method thereof | 信阳师范学院 | 2018-03-02 | — | — | CN | disclosed |