Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.49 |
| ▸ | HRH1 | P35367 | 4/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 3/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.40 |
| ▸ | CASR | P41180 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5401783 | 1.00 | MTNR1A (0.49) | MTNR1AMTNR1BHRH1ALOX5HTR2A | |
| SCHEMBL11543107 | 0.77 | MTNR1A (0.58) | MTNR1AMTNR1BHRH1HTR2AEPHX2 | |
| SCHEMBL2091811 | 0.77 | HRH1 (0.52) | MTNR1AMTNR1BHRH1ALOX5HTR2A | |
| Hydrochloric Acid SCHEMBL28569021 | 0.76 | HRH1 (0.50) | MTNR1AMTNR1BHRH1ALOX5HTR2A | |
| SCHEMBL8494351 | 0.73 | MTNR1A (0.52) | MTNR1AMTNR1BHRH1HTR2AEPHX2 | |
| SCHEMBL3674189 | 0.73 | CYP2D6 (0.54) | MTNR1AMTNR1BHRH1HTR2AEPHX2 | |
| SCHEMBL28355193 | 0.72 | CNR1 (0.55) | MTNR1AMTNR1BHRH1ALOX5CNR1 | |
| SCHEMBL4219820 | 0.72 | HRH1 (0.57) | MTNR1AMTNR1BHRH1HTR2AEPHX2 | |
| SCHEMBL9003508 | 0.71 | CES1 (0.50) | EPHX2KMT2APKM | |
| SCHEMBL9003513 | 0.71 | CES1 (0.50) | EPHX2KMT2APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7247645-B2 | Dihydropyridine derivatives | AJINOMOTO CO., INC. (JP) | 2007-07-24 | — | — | US | disclosed |