Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.46 |
| ▸ | FEN1 | P39748 | 1/20 | 0.46 |
| ▸ | SHBG | P04278 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MAPK13 | O15264 | 3/20 | 0.43 |
| ▸ | MAPK12 | P53778 | 3/20 | 0.43 |
| ▸ | MAPK11 | Q15759 | 3/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2935940 | 0.89 | GABRA1 (0.48) | HPGDTSHRHTTALDH1A1MAPT | |
| SCHEMBL333141 | 0.85 | CYP3A4 (0.55) | HPGDERCC5FEN1KMT2ACYP3A4 | |
| SCHEMBL29387256 | 0.85 | CYP3A4 (0.55) | HPGDERCC5FEN1KMT2ACYP3A4 | |
| SCHEMBL11616146 | 0.84 | HSD11B1 (0.47) | KMT2ACYP3A4TSHRHTTMAPK13 | |
| SCHEMBL25563177 | 0.83 | TSHR (0.59) | HPGDERCC5FEN1KMT2ACYP3A4 | |
| SCHEMBL10669335 | 0.83 | CYP3A4 (0.59) | HPGDERCC5FEN1KMT2ACYP3A4 | |
| SCHEMBL3953764 | 0.80 | ALDH1A1 (0.56) | KMT2ACYP3A4CYP2C9HTTMEN1 | |
| SCHEMBL6546961 | 0.80 | HPGD (0.47) | HPGDERCC5FEN1SHBGKMT2A | |
| SCHEMBL9461183 | 0.80 | HPGD (0.50) | HPGDKMT2ACYP3A4TSHRMEN1 | |
| SCHEMBL19834695 | 0.78 | MEN1 (0.42) | KMT2ACYP2C9TSHRHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9657043-B2 | Amine compound and use thereof for medical purposes | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2017-05-23 | — | — | US | disclosed |
| US-20150087620-A1 | AMINE COMPOUND AND USE THEREOF FOR MEDICAL PURPOSES | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2015-03-26 | — | — | US | disclosed |
| US-7208517-B1 | Endothelin antagonists | ABBOTT LABORTORIES (US) | 2007-04-24 | — | — | US | disclosed |
| WO-2002017912-A1 | ENDOTHELIN ANTAGONISTS | ABBOTT LABORATORIES (US) | 2002-03-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150087620-A1 | AMINE COMPOUND AND USE THEREOF FOR MEDICAL PURPOSES | HLA-B, HLA-A, HLA-C | HPGD 659/4885ERCC5 3662/4885FEN1 2936/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.