Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29556759 | 1.00 | ALDH1A1 (0.34) | ALDH1A1NPC1PLA2G1BNFKB1CASP3 | |
| Bromide SCHEMBL27651355 | 0.97 | ALDH1A1 (0.34) | ALDH1A1NPC1PLA2G1BNFKB1CASP3 | |
| Hydrochloric Acid SCHEMBL30925343 | 0.86 | NPC1 (0.37) | ALDH1A1NPC1PLA2G1BNFKB1CASP3 | |
| SCHEMBL18261204 | 0.81 | ALDH1A1 (0.37) | ALDH1A1NPC1PLA2G1BNFKB1CASP3 | |
| Hydrochloric Acid SCHEMBL4833338 | 0.81 | ESR1 (0.37) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL540937 | 0.81 | ALDH1A1 (0.34) | ALDH1A1NPC1PLA2G1BNFKB1CASP3 | |
| Hydrochloric Acid SCHEMBL27836242 | 0.81 | ALDH1A1 (0.34) | ALDH1A1NPC1PLA2G1BNFKB1CASP3 | |
| SCHEMBL6471558 | 0.79 | CYP1A2 (0.38) | ALDH1A1NPC1PLA2G1BNFKB1CASP3 | |
| SCHEMBL30497613 | 0.79 | ALDH1A1 (0.35) | ALDH1A1NPC1PLA2G1BNFKB1CASP3 | |
| SCHEMBL29556735 | 0.79 | CYP1A2 (0.38) | ALDH1A1NPC1PLA2G1BNFKB1CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 174 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101291960-B | Impact copolymer of propylene prepared in single reactor | TOTAL PETROCHEMICALS RES FELUY | 2012-11-07 | — | — | CN | claimed |
| CN-101668578-A | Process for the polymerization of olefins | TOTAL PETROCHEMICALS RES FELUY | 2010-03-10 | — | — | CN | claimed |
| CN-116199813-A | Long chain branched polypropylene and preparation method thereof | 中国科学院化学研究所 | 2023-06-02 | — | — | CN | disclosed |
| CN-111868116-B | Ethylene-alpha-olefin-nonconjugated polyene copolymer, process for producing the same, and use thereof | 三井化学株式会社 | 2022-12-09 | — | — | CN | disclosed |
| CN-111217950-B | Poly-alpha-olefin having uniform structure and method for preparing same | DL化学株式会社 | 2022-09-20 | — | — | CN | disclosed |
| CN-111249059-B | Tooth socket | 三井化学株式会社 | 2022-05-17 | — | — | CN | disclosed |
| CN-111265357-B | Tooth socket | 三井化学株式会社 | 2022-04-19 | — | — | CN | disclosed |
| CN-110312618-B | Laminated body | 三井化学株式会社 | 2021-09-07 | — | — | CN | disclosed |
| CN-110325360-B | Laminated body | 三井化学株式会社 | 2021-07-20 | — | — | CN | disclosed |
| CN-108712893-B | Mouthpiece, sheet for producing mouthpiece cover part, and method for producing mouthpiece | 三井化学株式会社 | 2021-02-19 | — | — | CN | disclosed |
| CN-111868116-A | Ethylene-alpha-olefin-nonconjugated polyene copolymer, process for producing the same, and use thereof | 三井化学株式会社 | 2020-10-30 | — | — | CN | disclosed |
| CN-1791619-A | Ethylene polymer | MITSUI CHEMICALS INC (JP) | 2006-06-21 | — | — | CN | disclosed |
| CN-1782044-A | Synthetic lubricating oil and lubricating oil composition | MITSUI CHEMICALS INC (JP) | 2006-06-07 | — | — | CN | disclosed |
| US-20060116303-A1 | decene-ethylene copolymer, zirconium, titanium or hafnium fluorene-containing complexes, organometallics; improved high thermal oxidation stability, viscosity index, low-temperature viscosity properties and shear stability | MITSUI CHEMICALS, INC. (JP) | 2006-06-01 | — | — | US | disclosed |
| CN-1759128-A | Propylene copolymer, polypropylene composition and use thereof, transition metal compound and olefin polymerization catalyst | MITSUI CHEMICALS INC (JP) | 2006-04-12 | — | — | CN | disclosed |
| EP-1632505-A1 | ETHYLENE POLYMER | Mitsui Chemicals, Inc. (JP) | 2006-03-08 | — | — | EP | disclosed |
| CN-1732189-A | Ethylene polymer and molded article obtained therefrom | MITSUI CHEMICALS INC (JP) | 2006-02-08 | — | — | CN | disclosed |
| EP-1614699-A1 | PROPYLENE COPOLYMER, POLYPROPYLENE COMPOSITION, USE THEREOF, TRANSITION METAL COMPOUNDS, AND CATALYSTS FOR OLEFIN POLYMERIZATION | Mitsui Chemicals, Inc. (JP) | 2006-01-11 | — | — | EP | disclosed |
| US-20050228155-A1 | Metallocene compound, process for preparing metallocene compund, olefin polymerization catalyst, process for preparing polyolefin, and polyolefin | MITSUI CHEMICALS, INC. (JP) | 2005-10-13 | — | — | US | disclosed |
| EP-1138687-A1 | METALLOCENE COMPOUND, PROCESS FOR PRODUCING METALLOCENE COMPOUND, OLEFIN POLYMERIZATION CATALYST, PROCESS FOR PRODUCING POLYOLEFIN, AND POLYOLEFIN | Mitsui Chemicals, Inc. (JP) | 2001-10-04 | — | — | EP | disclosed |