Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18261204 | 0.81 | ALDH1A1 (0.37) | ALDH1A1NPC1PLA2G1BNFKB1CASP3 | |
| Hydrochloric Acid SCHEMBL27836242 | 0.81 | ALDH1A1 (0.34) | ALDH1A1NPC1PLA2G1BNFKB1CASP3 | |
| Hydrochloric Acid SCHEMBL540223 | 0.81 | ALDH1A1 (0.34) | ALDH1A1NPC1PLA2G1BNFKB1CASP3 | |
| Hydrochloric Acid SCHEMBL29556759 | 0.81 | ALDH1A1 (0.34) | ALDH1A1NPC1PLA2G1BNFKB1CASP3 | |
| SCHEMBL29556735 | 0.79 | CYP1A2 (0.38) | ALDH1A1NPC1PLA2G1BNFKB1CASP3 | |
| SCHEMBL6471558 | 0.79 | CYP1A2 (0.38) | ALDH1A1NPC1PLA2G1BNFKB1CASP3 | |
| SCHEMBL27706470 | 0.79 | ALDH1A1 (0.35) | ALDH1A1NPC1PLA2G1BNFKB1CASP3 | |
| SCHEMBL945914 | 0.79 | ALDH1A1 (0.35) | ALDH1A1NPC1PLA2G1BNFKB1CASP3 | |
| SCHEMBL30497613 | 0.79 | ALDH1A1 (0.35) | ALDH1A1NPC1PLA2G1BNFKB1CASP3 | |
| SCHEMBL540390 | 0.79 | ALDH1A1 (0.35) | ALDH1A1NPC1PLA2G1BNFKB1CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106068291-B | Olefin-based resin, its manufacturing method and propylene resin composition | 三井化学株式会社 | 2019-03-12 | — | — | CN | disclosed |
| CN-109196039-A | Composition for thermoplastic elastomer, its manufacturing method and formed body | 三井化学株式会社 | 2019-01-11 | — | — | CN | disclosed |
| CN-106068291-A | Olefin-based resin, its manufacture method and propylene resin composition | 三井化学株式会社 | 2016-11-02 | — | — | CN | disclosed |
| CN-102666561-B | Transition metal complex, the cyclopentadiene compound of catalyst for trimerization and replacement | SUMITOMO CHEMICAL CO.,LTD. (JP) | 2015-11-25 | — | — | CN | disclosed |
| CN-102356100-B | Copolymer of olefin and conjugated diene and preparation method thereof | MITSU CHEMICALS INC | 2014-01-08 | — | — | CN | disclosed |
| CN-102666561-A | Transition metal complex, preparation method for said transition metal complex, trimerization catalyst, preparation method for 1-hexene, preparation method for ethylene polymer, substituted cyclopentadiene compound, and preparation method for said su | SUMITOMO CHEMICAL CO | 2012-09-12 | — | — | CN | disclosed |
| CN-102356100-A | Copolymer of olefin and conjugated diene and preparation method thereof | MITSUI CHEMICALS INC | 2012-02-15 | — | — | CN | disclosed |
| EP-2415792-A1 | COPOLYMER OF OLEFIN AND CONJUGATED DIENE, AND PROCESS FOR PRODUCING SAME | Mitsui Chemicals, Inc. (JP) | 2012-02-08 | — | — | EP | disclosed |