Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14578298 | 1.00 | SLC6A3 (0.43) | SLC6A3HPGDGAAMEN1KMT2A | |
| SCHEMBL10455907 | 1.00 | SLC6A3 (0.43) | SLC6A3HPGDGAAMEN1KMT2A | |
| SCHEMBL10136515 | 0.84 | SLC6A3 (0.44) | SLC6A3HPGDGAAMEN1KMT2A | |
| SCHEMBL8978498 | 0.83 | SLC6A3 (0.46) | SLC6A3HPGDGAAMEN1KMT2A | |
| SCHEMBL10455908 | 0.83 | SLC6A3 (0.46) | SLC6A3HPGDGAAMEN1KMT2A | |
| SCHEMBL29167883 | 0.80 | SLC6A3 (0.44) | SLC6A3HPGDGAAMEN1KMT2A | |
| SCHEMBL5410510 | 0.79 | SLC6A3 (0.44) | SLC6A3HPGDGAAMEN1KMT2A | |
| SCHEMBL5410516 | 0.79 | SLC6A3 (0.44) | SLC6A3HPGDGAAMEN1KMT2A | |
| SCHEMBL11719808 | 0.77 | SLC6A3 (0.46) | SLC6A3HPGDGAAMEN1KMT2A | |
| SCHEMBL13686149 | 0.77 | SLC6A3 (0.46) | SLC6A3HPGDGAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7173141-B2 | Chiral lactones | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2007-02-06 | — | — | US | disclosed |
| US-7173141-B2 | Chiral lactones | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2007-02-06 | — | — | US | disclosed |
| US-20060205816-A1 | Chiral lactones | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2006-09-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060205816-A1 | Chiral lactones | HSD11B2, HSD11B1, HSD17B2 | SLC6A3 4863/4885HPGD 171/4885GAA 277/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.