Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.55 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.55 |
| ▸ | CNR1 | P21554 | 2/20 | 0.46 |
| ▸ | CNR2 | P34972 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | SRC | P12931 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 3/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.44 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.44 |
| ▸ | CASR | P41180 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5415283 | 0.89 | MTNR1A (0.51) | MTNR1AMTNR1BCNR1CNR2CYP2D6 | |
| SCHEMBL5412330 | 0.87 | MTNR1A (0.50) | MTNR1AMTNR1BCNR1CNR2CYP2D6 | |
| SCHEMBL7252518 | 0.85 | RIPK1 (0.47) | MTNR1AMTNR1BCYP2D6SRCPOLB | |
| SCHEMBL7639003 | 0.84 | KMT2A (0.53) | MTNR1AMTNR1BCNR1CNR2POLB | |
| SCHEMBL10409938 | 0.83 | HTR2A (0.53) | MTNR1AMTNR1BCNR1CNR2EPHX2 | |
| SCHEMBL7640821 | 0.83 | TDP1 (0.51) | MTNR1AMTNR1BPOLBCASR | |
| SCHEMBL10409911 | 0.83 | HTR2A (0.49) | MTNR1AMTNR1BCNR1CNR2CYP2D6 | |
| SCHEMBL7638548 | 0.81 | MTNR1A (0.45) | MTNR1AMTNR1BCNR1CNR2CYP2D6 | |
| SCHEMBL5396760 | 0.81 | MTNR1A (0.47) | MTNR1AMTNR1BCNR1CNR2CYP2D6 | |
| SCHEMBL7640155 | 0.80 | ALDH1A1 (0.53) | MTNR1AMTNR1BCNR1LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7247645-B2 | Dihydropyridine derivatives | AJINOMOTO CO., INC. (JP) | 2007-07-24 | — | — | US | disclosed |