Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 4/20 | 0.48 |
| ▸ | NR1H3 | Q13133 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 5/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | HRH1 | P35367 | 2/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11701106 | 0.89 | NR1H2 (0.43) | NR1H2NR1H3ALDH1A1MEN1KMT2A | |
| SCHEMBL2595023 | 0.83 | LMNA (0.46) | ALDH1A1MEN1KMT2ALMNATRPA1 | |
| SCHEMBL14018422 | 0.82 | KDM4E (0.47) | NR1H2NR1H3ALDH1A1LMNATRPA1 | |
| SCHEMBL28794563 | 0.82 | KDM4E (0.47) | NR1H2NR1H3ALDH1A1LMNATRPA1 | |
| Hydrochloric Acid SCHEMBL2455720 | 0.81 | MEN1 (0.45) | ALDH1A1MEN1KMT2ALMNAHTR2A | |
| Bromide SCHEMBL6625831 | 0.81 | MEN1 (0.45) | NR1H2NR1H3ALDH1A1MEN1KMT2A | |
| SCHEMBL3730187 | 0.79 | MEN1 (0.44) | NR1H2NR1H3ALDH1A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL27845404 | 0.79 | MEN1 (0.44) | ALDH1A1MEN1KMT2ALMNAHTR2A | |
| SCHEMBL17803383 | 0.79 | TAAR1 (0.48) | ALDH1A1MEN1KMT2ALMNAHTR2A | |
| SCHEMBL17772935 | 0.79 | PGR (0.47) | ALDH1A1MEN1KMT2ALMNAHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7169777-B2 | Melanocortin receptor agonists | ELI LILLY AND COMPANY (US) | 2007-01-30 | — | — | US | disclosed |
| US-7169777-B2 | Melanocortin receptor agonists | ELI LILLY AND COMPANY (US) | 2007-01-30 | — | — | US | disclosed |
| US-20040116699-A1 | Melanocortin receptor agonists | ELI LILLY AND COMPANY | 2004-06-17 | — | — | US | disclosed |
| EP-1358163-A1 | MELANOCORTIN RECEPTOR AGONISTS | ELI LILLY AND COMPANY (US) | 2003-11-05 | — | — | EP | disclosed |
| WO-2002059095-A1 | MELANOCORTIN RECEPTOR AGONISTS | ELI LILLY AND COMPANY (US) | 2002-08-01 | — | — | WO | disclosed |