Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 known ✓ | Q99720 | 1/20 | 0.41 |
| ▸ | HTR2A known ✓ | P28223 | 3/20 | 0.40 |
| ▸ | HRH1 known ✓ | P35367 | 3/20 | 0.40 |
| ▸ | ADRA2A known ✓ | P08913 | 1/20 | 0.40 |
| ▸ | ADRA2B known ✓ | P18089 | 1/20 | 0.40 |
| ▸ | KCNH2 known ✓ | Q12809 | 1/20 | 0.40 |
| ▸ | KCNA5 known ✓ | P22460 | 1/20 | 0.37 |
| ▸ | OPRD1 known ✓ | P41143 | 1/20 | 0.36 |
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 known ✓ | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27845404 | 0.98 | MEN1 (0.44) | MEN1KMT2AALDH1A1LMNATDP1 | |
| SCHEMBL2595023 | 0.98 | LMNA (0.46) | MEN1KMT2AALDH1A1LMNATDP1 | |
| Bromide SCHEMBL6625831 | 0.96 | MEN1 (0.45) | MEN1KMT2AALDH1A1LMNATDP1 | |
| Hexane SCHEMBL28249674 | 0.92 | KCNH2 (0.45) | MEN1KMT2AALDH1A1LMNATDP1 | |
| Propylamine SCHEMBL28195200 | 0.91 | MEN1 (0.40) | MEN1KMT2AALDH1A1LMNATDP1 | |
| Styrene SCHEMBL28018470 | 0.86 | ALDH1A1 (0.45) | MEN1KMT2AALDH1A1LMNATDP1 | |
| SCHEMBL17803383 | 0.81 | TAAR1 (0.48) | MEN1KMT2AALDH1A1LMNASIGMAR1 | |
| SCHEMBL5403210 | 0.81 | NR1H2 (0.48) | MEN1KMT2AALDH1A1LMNASIGMAR1 | |
| SCHEMBL28279550 | 0.81 | LMNA (0.43) | LMNATDP1TRPM8SIGMAR1HTR2A | |
| SCHEMBL3730187 | 0.81 | MEN1 (0.44) | MEN1KMT2AALDH1A1LMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1970 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119390941-A | High-bonding-strength bio-based epoxy resin and synthesis method thereof | 烟台德邦科技股份有限公司 | 2025-02-07 | — | — | CN | claimed |
| CN-119306598-A | Catalyst composition, application thereof and synthetic method of cyhalofop-butyl | 江苏省农用激素工程技术研究中心有限公司 | 2025-01-14 | — | — | CN | claimed |
| CN-118718326-A | Intelligent fire extinguishing resin and preparation method thereof | 辽宁大学 | 2024-10-01 | — | — | CN | claimed |
| CN-115651318-B | Super-tough anti-seismic MPP power tube and preparation method thereof | 北方中意新材料（桐庐）有限公司 | 2024-07-19 | — | — | CN | claimed |
| CN-118239991-A | Preparation process of high-purity 2-amino-6-chloropurine nucleoside | 甘肃省化工研究院有限责任公司 | 2024-06-25 | — | — | CN | claimed |
| CN-114259996-B | Spherical rhenium directional adsorbent and application method thereof | 洛阳双罗铼材料科技有限公司 | 2024-03-19 | — | — | CN | claimed |
| CN-117511248-A | Preparation method of solvent orange 116 | 宜昌思创新材料科技有限公司 | 2024-02-06 | — | — | CN | claimed |
| CN-117487234-A | Low flexural modulus heat shrinkage label film for battery label and preparation method thereof | 江苏景宏新材料科技有限公司 | 2024-02-02 | — | — | CN | claimed |
| CN-116925129-A | Synthesis method of triphenyltin hydroxide | 浙江禾本科技股份有限公司 | 2023-10-24 | — | — | CN | claimed |
| CN-114214528-B | Preparation method of high-purity ammonium rhenate | 洛阳双罗铼材料科技有限公司 | 2023-05-30 | — | — | CN | claimed |
| CN-1075901-A | Composite phase transfer catalyst and preparation thereof and application | HUADONG COLLEGE OF CHEMICAL EN (CN) | 1993-09-08 | — | — | CN | claimed |
| CN-1075476-A | Preparation method of 2-chloro-5-methylpyridine | BAYER AG (DE) | 1993-08-25 | — | — | CN | claimed |
| CN-1015715-B | PREPN. OF RAT-KILLING PHOSPHORIC POISON BAIT AND ITS SERIES | LIAONING PROV CHEMICAL INDUSTR (CN) | 1992-03-04 | — | — | CN | claimed |
| CN-1010942-B | Synthetic method of cyhalothrin | CHENGDU ORGANIC CHEM INST (CN) | 1990-12-26 | — | — | CN | claimed |
| CN-1046736-A | Produce improving one's methods of 1-positive dodecyl aza cyclohepta-2-ketone | UNIV BEIJING NORMAL (CN) | 1990-11-07 | — | — | CN | claimed |
| CN-1046326-A | PREPARATION OF BIPHTHALIC ACID BY PHASE-TRANSFER CATALYZED OXIDATION METHOD FROM PHENANTHRENE | DALIAN SCIENCE AND EGNINEERING (CN) | 1990-10-24 | — | — | CN | claimed |
| CN-1040788-A | Synthesizing of polyaryl-sulfone type macromolecular monomer | UNIV JILIN (CN) | 1990-03-28 | — | — | CN | claimed |
| CN-1006009-B | Preparation method of two-equivalent yellow color former | 化学工业部沈阳化工研究院 | 1989-12-06 | — | — | CN | claimed |
| CN-1034708-A | A kind of synthetic method of fluoro-Cyano chrysanthemate | CHENGDU ORGANIC CHEM INST (CN) | 1989-08-16 | — | — | CN | claimed |
| CN-85100339-A | The preparation method of twice normality yellow colour developing | — | 1986-08-13 | — | — | CN | claimed |