Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | PIM1 | P11309 | 2/20 | 0.39 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.39 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | IKBKB | O14920 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.36 |
| ▸ | TOP1 | P11387 | 2/20 | 0.36 |
| ▸ | TOP2A | P11388 | 2/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3251791 | 0.84 | GAA (0.43) | ALDH1A1HTTGAAMAPTRAD52 | |
| SCHEMBL17264121 | 0.83 | ALDH1A1 (0.50) | ALDH1A1HTTGAAMAPTRAD52 | |
| SCHEMBL5390334 | 0.83 | ALDH1A1 (0.38) | HRH4ALDH1A1HTTGAAPIM1 | |
| SCHEMBL17265653 | 0.81 | MAPT (0.54) | ALDH1A1HTTGAAMAPTRAD52 | |
| SCHEMBL13537664 | 0.81 | PIM1 (0.42) | HRH4ALDH1A1HTTGAAPIM1 | |
| SCHEMBL26640483 | 0.81 | ALDH1A1 (0.48) | ALDH1A1HTTGAAMAPTRAD52 | |
| SCHEMBL5386929 | 0.80 | MAPT (0.58) | HRH4ALDH1A1HTTGAAMAPT | |
| SCHEMBL27584940 | 0.79 | GAA (0.43) | HRH4ALDH1A1HTTGAAPIM1 | |
| SCHEMBL15509139 | 0.78 | MAPT (0.59) | ALDH1A1HTTGAAMAPTRAD52 | |
| SCHEMBL5395255 | 0.77 | NR4A1 (0.49) | HRH4ALDH1A1HTTGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7179301-B2 | Dyeing compositions for keratinous fibers containing paraphenylenediamine derivatives with pyrrolidinyl group | L'OREAL S.A. (FR) | 2007-02-20 | — | — | US | claimed |
| US-7070629-B2 | Dye composition comprising at least one diaminopyrazole oxidation base, at least one paraphenylenediamine oxidation base comprising a cyclic amino group, and at least one coupler | L'OREAL, S.A. (FR) | 2006-07-04 | — | — | US | claimed |
| US-20040231066-A1 | Dyeing composition comprising a diaminopyrazole-type oxidation base, a paraphenylenediamine-type oxidation base with cyclic amino group and a coupling agent | L'OREAL S.A. (FR) | 2004-11-25 | — | — | US | claimed |
| EP-1432389-A1 | DYEING COMPOSITION COMPRISING A DIAMINOPYRAZOLE-TYPE OXIDATION BASE, A PARAPHENYLENEDIAMINE-TYPE OXIDATION BASE WITH CYCLIC AMINO GROUP AND A COUPLING AGENT | L'OREAL (FR) | 2004-06-30 | — | — | EP | claimed |
| US-20030093866-A1 | Dyeing compositions for keratinous fibres containing paraphenylenediamine derivatives with pyrrolidinyl group | L'OREAL S.A. (FR) | 2003-05-22 | — | — | US | claimed |
| WO-2003028689-A1 | DYEING COMPOSITION COMPRISING A DIAMINOPYRAZOLE-TYPE OXIDATION BASE, A PARAPHENYLENEDIAMINE-TYPE OXIDATION BASE WITH CYCLIC AMINO GROUP AND A COUPLING AGENT | L'OREAL (FR) | 2003-04-10 | — | — | WO | claimed |
| CN-1372459-A | Dyeing composition for keratinous fibres comprising a p-phenylenediamine derivative having a pyrrolidinyl group | OREAL (FR) | 2002-10-02 | — | — | CN | claimed |
| EP-1200052-A2 | DYEING COMPOSITIONS FOR KERATINOUS FIBRES CONTAINING PARAPHENYLENEDIAMINE DERIVATIVES WITH PYRROLIDINYL GROUP | L'OREAL (FR) | 2002-05-02 | — | — | EP | claimed |
| WO-2001068043-A2 | DYEING COMPOSITIONS FOR KERATINOUS FIBRES CONTAINING PARAPHENYLENEDIAMINE DERIVATIVES WITH PYRROLIDINYL GROUP | L'OREAL (FR) | 2001-09-20 | — | — | WO | claimed |
| US-7179301-B2 | Dyeing compositions for keratinous fibers containing paraphenylenediamine derivatives with pyrrolidinyl group | L'OREAL S.A. (FR) | 2007-02-20 | — | — | US | disclosed |
| US-7070629-B2 | Dye composition comprising at least one diaminopyrazole oxidation base, at least one paraphenylenediamine oxidation base comprising a cyclic amino group, and at least one coupler | L'OREAL, S.A. (FR) | 2006-07-04 | — | — | US | disclosed |
| US-20040231066-A1 | Dyeing composition comprising a diaminopyrazole-type oxidation base, a paraphenylenediamine-type oxidation base with cyclic amino group and a coupling agent | L'OREAL S.A. (FR) | 2004-11-25 | — | — | US | disclosed |
| CN-1532193-A | Dimethyl-[1-(4-nitrophenyl) pyrrolidine-3-yl] amine | �ź㴫 | 2004-09-29 | — | — | CN | disclosed |
| EP-1432389-A1 | DYEING COMPOSITION COMPRISING A DIAMINOPYRAZOLE-TYPE OXIDATION BASE, A PARAPHENYLENEDIAMINE-TYPE OXIDATION BASE WITH CYCLIC AMINO GROUP AND A COUPLING AGENT | L'OREAL (FR) | 2004-06-30 | — | — | EP | disclosed |
| US-20030093866-A1 | Dyeing compositions for keratinous fibres containing paraphenylenediamine derivatives with pyrrolidinyl group | L'OREAL S.A. (FR) | 2003-05-22 | — | — | US | disclosed |
| WO-2003028689-A1 | DYEING COMPOSITION COMPRISING A DIAMINOPYRAZOLE-TYPE OXIDATION BASE, A PARAPHENYLENEDIAMINE-TYPE OXIDATION BASE WITH CYCLIC AMINO GROUP AND A COUPLING AGENT | L'OREAL (FR) | 2003-04-10 | — | — | WO | disclosed |
| CN-1372459-A | Dyeing composition for keratinous fibres comprising a p-phenylenediamine derivative having a pyrrolidinyl group | OREAL (FR) | 2002-10-02 | — | — | CN | disclosed |
| EP-1200052-A2 | DYEING COMPOSITIONS FOR KERATINOUS FIBRES CONTAINING PARAPHENYLENEDIAMINE DERIVATIVES WITH PYRROLIDINYL GROUP | L'OREAL (FR) | 2002-05-02 | — | — | EP | disclosed |
| WO-2001068043-A2 | DYEING COMPOSITIONS FOR KERATINOUS FIBRES CONTAINING PARAPHENYLENEDIAMINE DERIVATIVES WITH PYRROLIDINYL GROUP | L'OREAL (FR) | 2001-09-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040231066-A1 | Dyeing composition comprising a diaminopyrazole-type oxidation base, a paraphenylenediamine-type oxidation base with cyclic amino group and a coupling agent | KRT18, AOC1, DPYD | HRH4 1473/4885ALDH1A1 446/4885HTT 3390/4885 |
| US-20030093866-A1 | Dyeing compositions for keratinous fibres containing paraphenylenediamine derivatives with pyrrolidinyl group | KRT18, CKAP4, KRTCAP2 | HRH4 2556/4885ALDH1A1 1172/4885HTT 2705/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.