Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 4/20 | 0.51 |
| ▸ | HSD17B2 | P37059 | 4/20 | 0.51 |
| ▸ | MGLL | Q99685 | 6/20 | 0.50 |
| ▸ | ESR1 | P03372 | 6/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5403661 | 1.00 | HSD17B1 (0.51) | HSD17B1HSD17B2MGLLESR1ESR2 | |
| SCHEMBL17329459 | 0.85 | L3MBTL1 (0.52) | MGLLESR1ESR2KDM4ELMNA | |
| SCHEMBL17329458 | 0.85 | L3MBTL1 (0.52) | MGLLESR1ESR2KDM4ELMNA | |
| SCHEMBL857363 | 0.78 | ESR1 (0.68) | HSD17B1HSD17B2MGLLESR1ESR2 | |
| SCHEMBL30635318 | 0.78 | ESR1 (0.68) | HSD17B1HSD17B2MGLLESR1ESR2 | |
| SCHEMBL4896554 | 0.77 | ESR1 (0.48) | HSD17B1HSD17B2MGLLESR1ESR2 | |
| SCHEMBL4897802 | 0.77 | HSD17B1 (0.50) | HSD17B1HSD17B2MGLLESR1ESR2 | |
| SCHEMBL4897806 | 0.77 | HSD17B1 (0.50) | HSD17B1HSD17B2MGLLESR1ESR2 | |
| SCHEMBL4896546 | 0.77 | ESR1 (0.48) | HSD17B1HSD17B2MGLLESR1ESR2 | |
| SCHEMBL4896777 | 0.74 | ALDH1A1 (0.58) | ESR1ESR2KDM4EALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7279600-B2 | Hydroxy-biphenyl-carbaldehyde oxime derivatives and their use as estrogenic agents | WYETH (US) | 2007-10-09 | — | — | US | disclosed |
| US-20050020676-A1 | Hydroxy-biphenyl-carbaldehyde oxime derivatives and their use as estrogenic agents | WYETH | 2005-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050020676-A1 | Hydroxy-biphenyl-carbaldehyde oxime derivatives and their use as estrogenic agents | ESR1, ESR2, ESRRB | HSD17B1 147/4885HSD17B2 102/4885MGLL 4128/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.