SCHEMBL5403701

SCHEMBL5403701

CC(C)(C)c1ccc(S(OS(=O)(=O)c2cc(Cl)ccc2Cl)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.49

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 8/20 0.49
KDM4E B2RXH2 1/20 0.43
FLT1 P17948 1/20 0.43
FLT4 P35916 1/20 0.43
KDR P35968 1/20 0.43
HSD17B2 P37059 2/20 0.41
NR1I2 O75469 5/20 0.40
CCR9 P51686 1/20 0.40
HSD17B3 P37058 1/20 0.39
FBP1 P09467 1/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL561670 0.89 KDM4E (0.48) KDM4EFLT1FLT4KDRMEN1
SCHEMBL3159089 0.87 KDM4E (0.45) KDM4EFLT1FLT4KDRKMT2A
SCHEMBL5408753 0.87 KDM4E (0.45) KDM4EFLT1FLT4KDRKMT2A
SCHEMBL5400315 0.87 HSD11B1 (0.48) HSD11B1FLT1FLT4KDRHSD17B2
SCHEMBL5404426 0.84 KDM4E (0.42) KDM4E
SCHEMBL451539 0.80 HSD11B1 (0.53) HSD11B1KDM4EHSD17B2HSD17B3MEN1
SCHEMBL2634260 0.80 HSD11B1 (0.53) HSD11B1KDM4EHSD17B2HSD17B3MEN1
SCHEMBL5408918 0.79 KDM4E (0.42) KDM4EMEN1KMT2A
SCHEMBL5412319 0.78 KDM4E (0.41) HSD11B1KDM4EFBP1MEN1KMT2A
SCHEMBL3195800 0.77 HSD11B1 (0.42) HSD11B1NR1I2HSD17B3MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7312014-B2 Poly(p-hydroxystyrene/styrene/alkyl acrylate) terpolymer derivative and acid generator comprising triphenylsulfonium benzenesulfonate derivative; forming positive pattern using transcription technology in high vacuum with irradiated energy such as electron beam, extreme ultraviolet ray and X-ray WAKO PURE CHEMICAL INDUSTRIES LTD. (JP) 2007-12-25 US disclosed
US-6949329-B2 Pattern formation method MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 2005-09-27 US disclosed
US-20040170918-A1 Poly(p-hydroxystyrene/styrene/alkyl acrylate) terpolymer derivative and acid generator comprising triphenylsulfonium benzenesulfonate derivative; forming positive pattern using transcription technology in high vacuum with irradiated energy such as electron beam, extreme ultraviolet ray and X-ray WAKO PURE CHEMICAL INDUSTRIES LTD. (JP) 2004-09-02 US disclosed
EP-1406123-A1 RESIST COMPOSITIONS Wako Pure Chemical Industries, Ltd. (JP) 2004-04-07 EP disclosed
US-20030017425-A1 Pattern formation method MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 2003-01-23 US disclosed