Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 7/20 | 0.36 |
| ▸ | PRKACA | P17612 | 1/20 | 0.35 |
| ▸ | PRKACG | P22612 | 1/20 | 0.35 |
| ▸ | PRKACB | P22694 | 1/20 | 0.35 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5394438 | 0.82 | KMT2A (0.39) | KMT2APOLBCACNA2D1CACNA1BCACNB1 | |
| SCHEMBL5417237 | 0.79 | KMT2A (0.44) | KMT2APOLBCYP2C9CYP2C19 | |
| SCHEMBL5403953 | 0.78 | NPSR1 (0.52) | LTA4H | |
| SCHEMBL5403944 | 0.78 | NPSR1 (0.52) | LTA4H | |
| SCHEMBL5398650 | 0.74 | KMT2A (0.40) | KMT2APOLBCACNA2D1CACNA1BCACNB1 | |
| SCHEMBL5414432 | 0.73 | KMT2A (0.35) | KMT2APOLBHTR1AHTR1DHTR2A | |
| SCHEMBL5404020 | 0.73 | LTA4H (0.44) | KMT2APOLBCACNA1BLTA4H | |
| SCHEMBL5403956 | 0.72 | SLC6A3 (0.38) | — | |
| SCHEMBL5403560 | 0.72 | CYP1A2 (0.42) | KMT2ACACNA1BCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL5394447 | 0.71 | KMT2A (0.33) | KMT2APOLBPRKACAPRKACGPRKACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7169782-B2 | Aryl substituted thiazolidinones and the use thereof | EURO-CELTIQUE S.A. (LU) | 2007-01-30 | — | — | US | claimed |