Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 15/20 | 0.38 |
| ▸ | CTSL | P07711 | 2/20 | 0.35 |
| ▸ | CTSK | P43235 | 2/20 | 0.35 |
| ▸ | AMPD2 | Q01433 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3023911 | 0.76 | CTSS (0.50) | OPRM1OPRL1OPRK1CTSSCTSL | |
| SCHEMBL6685463 | 0.69 | CTSS (0.43) | OPRM1OPRL1OPRK1CTSSCTSL | |
| SCHEMBL3007945 | 0.67 | CTSS (0.55) | OPRM1OPRL1OPRK1CTSSCTSL | |
| SCHEMBL4801079 | 0.67 | CTSS (0.55) | OPRM1OPRL1OPRK1CTSSCTSL | |
| SCHEMBL6685915 | 0.60 | RAB9A (0.35) | OPRL1 | |
| SCHEMBL6685923 | 0.60 | RAB9A (0.38) | CTSSCTSLCTSK | |
| SCHEMBL4798400 | 0.59 | CTSS (0.55) | CTSSCTSLCTSK | |
| SCHEMBL3024687 | 0.59 | CTSS (0.39) | OPRM1OPRL1OPRK1CTSSCTSL | |
| SCHEMBL4799862 | 0.59 | CTSS (0.39) | OPRM1OPRL1OPRK1CTSSCTSL | |
| SCHEMBL6690873 | 0.59 | RAB9A (0.40) | OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1658267-A4 | INHIBITORS OF CATHEPSIN S | IRM LLC (BM) | 2007-08-01 | — | — | EP | claimed |
| JP-2007502836-A | — | — | 2007-02-15 | — | — | JP | claimed |
| EP-1658267-A2 | INHIBITORS OF CATHEPSIN S | IRM LLC (BM) | 2006-05-24 | — | — | EP | claimed |
| WO-2005034848-A2 | INHIBITORS OF CATHEPSIN S | IRM LLC (BM) | 2005-04-21 | — | — | WO | claimed |
| EP-1658267-A4 | INHIBITORS OF CATHEPSIN S | IRM LLC (BM) | 2007-08-01 | — | — | EP | disclosed |
| EP-1658267-A2 | INHIBITORS OF CATHEPSIN S | IRM LLC (BM) | 2006-05-24 | — | — | EP | disclosed |
| WO-2005034848-A2 | INHIBITORS OF CATHEPSIN S | IRM LLC (BM) | 2005-04-21 | — | — | WO | disclosed |