Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 7/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | KLK7 | P49862 | 3/20 | 0.37 |
| ▸ | CTSL | P07711 | 4/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6693494 | 0.88 | SLC6A9 (0.37) | RAB9ANPC1EPHX1 | |
| SCHEMBL6693570 | 0.87 | CA2 (0.44) | RAB9APOLB | |
| SCHEMBL5409955 | 0.87 | EPHX2 (0.47) | RAB9APOLBCTSSNPC1EPHX1 | |
| SCHEMBL6693491 | 0.87 | NPC1 (0.42) | RAB9ASMN1; SMN2NPC1MGLL | |
| SCHEMBL6687814 | 0.87 | EPHX1 (0.40) | RAB9ANPC1EPHX1 | |
| SCHEMBL6685915 | 0.86 | RAB9A (0.35) | RAB9APOLBSMN1; SMN2NPC1 | |
| SCHEMBL6693564 | 0.86 | CDK1 (0.37) | CTSSHSD11B1 | |
| SCHEMBL6690542 | 0.86 | RORC (0.41) | EPHX1 | |
| SCHEMBL5404160 | 0.85 | EPHX2 (0.46) | RAB9APOLBCTSSNPC1EPHX1 | |
| SCHEMBL6687352 | 0.85 | MAPT (0.45) | POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004084843-A2 | INHIBITORS OF CATHEPSIN S | IRM LLC (BM) | 2004-10-07 | — | — | WO | disclosed |