Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | CA9 | Q16790 | 3/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA7 | P43166 | 2/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.43 |
| ▸ | CDC25B | P30305 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1307735 | 0.98 | TSHR (0.47) | TSHRCA1CA9CA12CA2 | |
| SCHEMBL2964437 | 0.96 | TSHR (0.48) | TSHRCA1CA9CA12CA2 | |
| SCHEMBL28320390 | 0.81 | ALDH1A1 (0.52) | TSHRCA1CA9TDP1MEN1 | |
| SCHEMBL27828903 | 0.79 | TSHR (0.54) | TSHRTDP1LMNASMN1; SMN2KDM4E | |
| SCHEMBL6553295 | 0.79 | TSHR (0.50) | TSHRMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL28784449 | 0.79 | LMNA (0.53) | TSHRCA1CA9CA12CA2 | |
| Fluoride SCHEMBL28135103 | 0.77 | TSHR (0.48) | TSHRMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL28267649 | 0.76 | LMNA (0.55) | TSHRCA1CA9CA12CA2 | |
| SCHEMBL9770256 | 0.76 | TSHR (0.57) | TSHRCA1CA9CA12CA2 | |
| SCHEMBL9770279 | 0.76 | TSHR (0.57) | TSHRCA1CA9CA12CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3941206-A1 | NEW USES OF A MUTATED LACTONASE, AND COMPOSITIONS | Fondation Méditerranée Infection (FR) | 2022-01-26 | — | — | EP | claimed |
| WO-2020187861-A1 | NEW USES OF A MUTATED LACTONASE, AND COMPOSITIONS | FONDATION MEDITERRANEE INFECTION (FR) | 2020-09-24 | — | — | WO | claimed |
| JP-1230523-A | — | — | None | — | — | JP | disclosed |
| US-20250304931-A1 | NOVEL MUTATED LACTONASE ENZYMES, COMPOSITIONS CONTAINING THEM AND USES THEREOF | GENE AND GREEN TK (FR) | 2025-10-02 | — | — | US | disclosed |
| WO-2025078478-A1 | CANDIDA AFRICANA FOR USE IN THE TREATMENT OF CANCER | AB MAURI (UK) LTD (GB) | 2025-04-17 | — | — | WO | disclosed |
| US-20230193225-A1 | NEW USES OF A MUTATED LACTONASE, AND COMPOSITIONS | AIX-MARSEILLE UNIVERSITE (FR) | 2023-06-22 | — | — | US | disclosed |
| EP-3941206-A1 | NEW USES OF A MUTATED LACTONASE, AND COMPOSITIONS | Fondation Méditerranée Infection (FR) | 2022-01-26 | — | — | EP | disclosed |
| WO-2020187861-A1 | NEW USES OF A MUTATED LACTONASE, AND COMPOSITIONS | FONDATION MEDITERRANEE INFECTION (FR) | 2020-09-24 | — | — | WO | disclosed |
| CN-109072303-A | Anti-TNF antibodies, compositions, methods and uses for treating or preventing type 1 diabetes | 詹森生物科技公司 | 2018-12-21 | — | — | CN | disclosed |
| CN-105050590-B | Two layers of divergence type eye drops containing saualane | 千寿制药株式会社 | 2018-01-19 | — | — | CN | disclosed |
| US-20150284674-A1 | CAMPYLOBACTER BACTERIA AND DETECTION | THE SECRETARY OF STATE FOR ENIVORNMENT, FOOD & RURAL AFFAIRS (GB) | 2015-10-08 | — | — | US | disclosed |
| JP-H01230523-A | INACTIVATED VACCINE AND ITS PREPARATION | BEECHAM INC | 1989-09-14 | — | — | JP | disclosed |
| CN-1031233-A | Antiviral compound | WELLCOME FOUND (GB) | 1989-02-22 | — | — | CN | disclosed |
| CN-87104581-A | The monoclonal antibody of resisting pseudomonas aeruginosa flagellum | — | 1988-09-21 | — | — | CN | disclosed |
| CN-86106632-A | Acquired Immunodeficiency Syndrome (AIDS) Vaccine | — | 1987-05-13 | — | — | CN | disclosed |
| CN-85107032-A | The preparation of ruthenium complex and application | — | 1987-04-01 | — | — | CN | disclosed |
| CN-86104525-A | The analytical approach of human interleukin-2 and reagent | — | 1987-02-25 | — | — | CN | disclosed |
| CN-85107805-A | Manufacture method as N-alkenyl-3-hydroxy benzo [b] the thiophene-2-carboxamide derivatives derivative of dual-purpose cyclooxygenase and lipoxidase inhibitor | — | 1986-12-31 | — | — | CN | disclosed |
| US-4252826-A | CARBOXYLATE OF A METHYL POLYETHOXYLATED GLUCOSIDE AND A PRESERVATIVE AGENT | L'OREAL (FR) | 1981-02-24 | — | — | US | disclosed |
| US-4188466-A | BY ENZYMATIC HYDROLYSIS | I.N.R.A. (FR) | 1980-02-12 | — | — | US | disclosed |