SCHEMBL1307735

SCHEMBL1307735

CCOC(=S)c1ccccc1O.[Hg]

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.47
CA1 P00915 3/20 0.44
CA9 Q16790 3/20 0.44
CA12 O43570 2/20 0.44
CA2 P00918 2/20 0.44
CA7 P43166 2/20 0.44
CA14 Q9ULX7 2/20 0.44
CDC25B P30305 1/20 0.43
TDP1 Q9NUW8 2/20 0.42
SIRT5 Q9NXA8 1/20 0.41
MEN1 O00255 4/20 0.41
KMT2A Q03164 4/20 0.41
LMNA P02545 2/20 0.41
KDM4E B2RXH2 3/20 0.41
ALDH1A1 P00352 2/20 0.41
HSD17B10 Q99714 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.40
HPGD P15428 2/20 0.40
GAA P10253 1/20 0.40
RECQL P46063 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5404185 0.98 TSHR (0.46) TSHRCA1CA9CA12CA2
SCHEMBL2964437 0.98 TSHR (0.48) TSHRCA1CA9CA12CA2
SCHEMBL28320390 0.83 ALDH1A1 (0.52) TSHRCA1CA9TDP1MEN1
SCHEMBL27828903 0.80 TSHR (0.54) TSHRTDP1LMNAKDM4EALDH1A1
SCHEMBL6553295 0.80 TSHR (0.50) TSHRMEN1KMT2ALMNAALDH1A1
Fluoride SCHEMBL28135103 0.78 TSHR (0.48) TSHRMEN1KMT2ALMNAALDH1A1
SCHEMBL28267649 0.78 LMNA (0.55) TSHRCA1CA9CA12CA2
SCHEMBL9770279 0.78 TSHR (0.57) TSHRCA1CA9CA12CA2
SCHEMBL9770256 0.78 TSHR (0.57) TSHRCA1CA9CA12CA2
SCHEMBL59256 0.78 TSHR (0.57) TSHRCA1CA9CA12CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260138353-A1 ABSORBENT ARTICLE WITH PATTERNED ACTIVE MATERIAL ONTEX BV (BE) 2026-05-21 US disclosed
WO-2023222737-A1 ABSORBENT ARTICLE WITH PATTERNED ACTIVE MATERIAL ONTEX BV (BE) 2023-11-23 WO disclosed
EP-4279043-A1 ABSORBENT ARTICLE WITH PATTERNED ACTIVE MATERIAL Ontex BV (BE) 2023-11-22 EP disclosed
CN-108431024-A 3 type circovirus immunogenic composition of pig and its preparation and application 堪萨斯州立大学研究基金会 2018-08-21 CN disclosed
US-9932687-B2 High throughput screening of crystallization of materials CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2018-04-03 US disclosed
CN-107427572-A The vaccine of new pig hepato-encephalomyelitis virus and diagnosis 弗吉尼亚暨州立大学知识产权公司 2017-12-01 CN disclosed
US-9555150-B2 Absorbent articles comprising an organic zinc salt and an anti-bacterial agent or alkali metal chloride or alkaline earth metal chloride SCA HYGIENE PRODUCTS AB (SE) 2017-01-31 US disclosed
US-20160184824-A1 HIGH THROUGHPUT SCREENING OF CRYSTALLIZATION OF MATERIALS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2016-06-30 US disclosed
US-9205423-B2 High throughput screening of crystallization of materials CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2015-12-08 US disclosed
US-8709153-B2 Microfludic protein crystallography techniques CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2014-04-29 US disclosed
EP-1212365-A2 CRYSTAL STRUCTURES OF DOMAINS OF RECEPTOR PROTEIN TYROSINE KINASES AND THEIR LIGANDS NEW YORK UNIVERSITY SCHOOL OF MEDICINE (US) 2002-06-12 EP disclosed
EP-0721773-B1 Dental composition for relieving dentin hypersensitivity SUN MEDICAL CO LTD (JP) 2002-03-27 EP disclosed
WO-2001038393-A1 POLYPEPTIDES DERIVED FROM VITAMIN D NUCLEAR RECEPTOR, AND THEIR USES IN PARTICULAR FOR SCREENING VITAMIN D ANALOGUES CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2001-05-31 WO disclosed
WO-2001016181-A2 CRYSTAL STRUCTURES OF DOMAINS OF RECEPTOR PROTEIN TYROSINE KINASES AND THEIR LIGANDS NEW YORK UNIVERSITY SCHOOL OF MEDICINE (US) 2001-03-08 WO disclosed
US-5879663-A Dental composition for dentin hypersensitivity SUN MEDICAL CO., LTD. (JP) 1999-03-09 US disclosed
US-5766328-A Dental composition for relieving dentin hypersensitivity SUN MEDICAL CO., LTD. (JP) 1998-06-16 US disclosed
EP-0744171-A1 DENTAL COMPOSITION FOR HYPERSENSITIVE DENTIN SUN MEDICAL CO., LTD. (JP) 1996-11-27 EP disclosed
EP-0721773-A2 Dental composition for relieving dentin hypersensitivity SUN MEDICAL CO., LTD. (JP) 1996-07-17 EP disclosed
WO-1990012565-A1 WATER-CONTAINING FORMULATIONS WITH PHOSPHOLIPIDS NATTERMANN, A. & CIE. GMBH (DE) 1990-11-01 WO disclosed
US-4482759-A Fungicidally active benzhydrol derivatives DEGUSSA AKTIENGESELLSCHAFT (DE) 1984-11-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260138353-A1 ABSORBENT ARTICLE WITH PATTERNED ACTIVE MATERIAL CUTA, AXIN2, CTNNA1 TSHR 4824/4885CA1 574/4885CA9 237/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.