Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.55 |
| ▸ | SLC12A5 | Q9H2X9 | 1/20 | 0.55 |
| ▸ | PTGDR2 | Q9Y5Y4 | 6/20 | 0.54 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | CTSG | P08311 | 1/20 | 0.53 |
| ▸ | CMA1 | P23946 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.52 |
| ▸ | AR | P10275 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5405060 | 0.92 | CMA1 (0.60) | KMT2ASLC12A2SLC12A5PTGDR2HCRTR1 | |
| SCHEMBL5622412 | 0.83 | CTSG (0.57) | KMT2APTGDR2HCRTR1CTSGCMA1 | |
| SCHEMBL5620546 | 0.82 | CMA1 (0.54) | KMT2ASLC12A2SLC12A5PTGDR2HCRTR1 | |
| SCHEMBL5622802 | 0.81 | CTSG (0.71) | KMT2APTGDR2HCRTR1CTSGCMA1 | |
| SCHEMBL5621193 | 0.80 | CTSG (0.60) | PTGDR2HCRTR1MAPK1CTSGCMA1 | |
| SCHEMBL14577952 | 0.80 | PTGDR2 (0.67) | PTGDR2CTSGCMA1L3MBTL1SMN1; SMN2 | |
| SCHEMBL5621097 | 0.80 | CTSG (0.60) | KMT2ASLC12A2SLC12A5PTGDR2HCRTR1 | |
| SCHEMBL4307028 | 0.78 | SLC12A2 (0.67) | KMT2ASLC12A2SLC12A5PTGDR2HCRTR1 | |
| SCHEMBL7027470 | 0.77 | SLC12A2 (0.66) | KMT2ASLC12A2SLC12A5PTGDR2HCRTR1 | |
| SCHEMBL7027475 | 0.77 | SLC12A2 (0.66) | KMT2ASLC12A2SLC12A5PTGDR2HCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7176320-B2 | Benzimidazole derivative | TEIJIN LIMITED (JP) | 2007-02-13 | — | — | US | disclosed |
| US-20050267148-A1 | Benzimidazole derivative | TEIJIN LIMITED | 2005-12-01 | — | — | US | disclosed |
| US-20040162311-A1 | Benzimidazole derivative | TEIJIN LIMITED | 2004-08-19 | — | — | US | disclosed |
| US-20040010004-A1 | Benzimidazole derivatives | TEIJIN LIMITED (JP) | 2004-01-15 | — | — | US | disclosed |
| EP-1249450-A1 | BENZIMIDAZOLE DERIVATIVES | TEIJIN LIMITED (JP) | 2002-10-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040162311-A1 | Benzimidazole derivative | CMA1, CBR3, CBR1 | KMT2A 1949/4885SLC12A2 2961/4885SLC12A5 3485/4885 |
| US-20040010004-A1 | Benzimidazole derivatives | CMA1, CBR3, CBR1 | KMT2A 1860/4885SLC12A2 2977/4885SLC12A5 3517/4885 |
| US-20050267148-A1 | Benzimidazole derivative | CMA1, SERPINB1, TPSAB1 | KMT2A 1893/4885SLC12A2 2094/4885SLC12A5 1743/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.