SCHEMBL5404993

SCHEMBL5404993

CCC(C(=O)O)[Si](C)(C)O

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CHRM1 P11229 1/20 0.35
AKR1A1 P14550 1/20 0.35
CHRM3 P20309 1/20 0.35
HTR2A P28223 1/20 0.35
HTR2C P28335 1/20 0.35
ADRA1A P35348 1/20 0.35
HRH1 P35367 1/20 0.35
DRD3 P35462 1/20 0.35
SLC6A3 Q01959 1/20 0.35
HDAC1 Q13547 1/20 0.35
HDAC2 Q92769 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
CA2 P00918 1/20 0.34
MAPK1 P28482 1/20 0.34
SLC1A3 P43003 1/20 0.33
SLC1A2 P43004 1/20 0.33
SLC1A1 P43005 1/20 0.33
FFAR3 O14843 1/20 0.32
TP53 P04637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL654433 0.81 CHRM1 (0.36) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL2783708 0.75 CA2 (0.32) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL5576560 0.74 SLC1A3 (0.38) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL5067300 0.72 CA2 (0.30) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL1971029 0.70 CA2 (0.32) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL7039074 0.67 FFAR3 (0.30) FFAR3
SCHEMBL7034669 0.67 FFAR3 (0.30) FFAR3
Ethylmalonate SCHEMBL107241 0.64
SCHEMBL5003457 0.63 TDP1 (0.43) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL4319153 0.63 TDP1 (0.43) CHRM1AKR1A1CHRM3HTR2AHTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7157543-B2 Block polyorganosiloxane block organomer polymers and release agents EASTMAN KODAK COMPANY (US) 2007-01-02 US disclosed
US-7084202-B2 Molecular complexes and release agents EASTMAN KODAK COMPANY (US) 2006-08-01 US disclosed
US-20050182206-A1 Block polyorganosiloxane block organomer polymers and release agents KODAK PHILIPPINES LTD. 2005-08-18 US disclosed
US-6894137-B2 Block polyorganosiloxane block organomer polymers and release agents EASMAN KODAK COMPANY (US) 2005-05-17 US disclosed
US-20030232945-A1 Molecular complexes and release agents FAR EAST DEVELOPMENT LTD. 2003-12-18 US disclosed
US-20030232948-A1 Block polyorganosiloxane block organomer polymers and release agents BANK OF AMERICA, N.A., AS AGENT 2003-12-18 US disclosed