SCHEMBL654433

SCHEMBL654433

CCC(C(=O)O)[Si](C)(C)C

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM1 P11229 1/20 0.36
AKR1A1 P14550 1/20 0.36
CHRM3 P20309 1/20 0.36
HTR2A P28223 1/20 0.36
HTR2C P28335 1/20 0.36
ADRA1A P35348 1/20 0.36
HRH1 P35367 1/20 0.36
DRD3 P35462 1/20 0.36
SLC6A3 Q01959 1/20 0.36
HDAC1 Q13547 1/20 0.36
HDAC2 Q92769 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
CA2 P00918 1/20 0.36
MAPK1 P28482 1/20 0.36
SLC1A3 P43003 1/20 0.34
SLC1A2 P43004 1/20 0.34
SLC1A1 P43005 1/20 0.34
FFAR3 O14843 1/20 0.33
TP53 P04637 1/20 0.32
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5403967 0.81 CHRM1 (0.35) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL5404993 0.81 CHRM1 (0.35) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL7039074 0.79 FFAR3 (0.30) FFAR3
SCHEMBL7034669 0.79 FFAR3 (0.30) FFAR3
SCHEMBL2783708 0.77 CA2 (0.32) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL5003457 0.76 TDP1 (0.43) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL4319153 0.76 TDP1 (0.43) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL5576560 0.76 SLC1A3 (0.38) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL28897924 0.75
SCHEMBL8140400 0.74 GPR84 (0.52) CA2MAPK1SLC1A2SLC1A1GPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3281941-B1 PROCESS FOR PREPARING 2-(5-BROMO-4-(1-CYCLOPROPYLNAPHTHALEN-4-YL)-4H-1,2,4-TRIAZOL-3-YLTHIO)ACETIC ACID ZENTIVA KS (CZ) 2019-07-24 EP claimed
EP-2014797-A2 Coating composition for interconnection part of electrode and plasma display panel including the same Samsung SDI Co., Ltd. (KR) 2009-01-14 EP claimed
US-20080303439-A1 Coating composition for interconnection part of electrode and plasma display panel including the same SAMSUNG SDI CO., LTD., A CORP. OF THE REPUBLIC OF KOREA (KR) 2008-12-11 US claimed
EP-1343766-B1 CYCLIZATION PROCESS STEP IN THE MAKING OF QUINOLONES AND NAPHTHYRIDINES PROCTER & GAMBLE (US) 2005-07-27 EP claimed
EP-1343766-A1 CYCLIZATION PROCESS STEP IN THE MAKING OF QUINOLONES AND NAPHTHYRIDINES THE PROCTER & GAMBLE COMPANY (US) 2003-09-17 EP claimed
WO-2002048113-A1 CYCLIZATION PROCESS STEP IN THE MAKING OF QUINOLONES AND NAPHTHYRIDINES THE PROCTER & GAMBLE COMPANY (US) 2002-06-20 WO claimed
US-5892008-A Process for the preparation of 6-O-methyl erythromycin a using 9-hydroxy erythromycin derivatives ABBOTT LABORATORIES (US) 1999-04-06 US claimed
EP-0700926-B1 Process for the preparation of gestodene IND CHIMICA SRL (IT) 1998-11-04 EP claimed
US-12403437-B2 Method for producing nanodiamonds doped with group 14 element, and method for purifying same DAICEL CORPORATION (JP) 2025-09-02 US disclosed
US-12351463-B2 Heteroatom-doped nanodiamond DAICEL CORPORATION (JP) 2025-07-08 US disclosed
CN-113631252-B Method for producing and purifying nanodiamond doped with carbon group element 株式会社大赛璐 2025-05-23 CN disclosed
US-20250002355-A1 HETEROATOM-DOPED NANODIAMOND PARTICLES AND METHOD FOR PRODUCING HETEROATOM-DOPED NANODIAMOND PARTICLES DAICEL CORPORATION (JP) 2025-01-02 US disclosed
WO-2024219059-A1 NV CENTER-CONTAINING NANODIAMOND PARTICLE AND METHOD FOR PRODUCING SAME 株式会社ダイセル 2024-10-24 WO disclosed
EP-4382481-A1 HETEROATOM-DOPED NANODIAMOND PARTICLES AND METHOD FOR PRODUCING HETEROATOM-DOPED NANODIAMOND PARTICLES Daicel Corporation (JP) 2024-06-12 EP disclosed
US-5714488-A FOR TREATMENT OF ALLERGIC AND INFLAMMATORY DISEASE STATES ABBOTT LABORATORIES (US) 1998-02-03 US disclosed
WO-1997012939-A1 ORGANOPOLYSILOXANE COMPOUNDS CROSS-LINKABLE BY CLEAVING OF ALCOHOLS TO FORM ELASTOMERS WACKER-CHEMIE GMBH (DE) 1997-04-10 WO disclosed
US-5453509-A Functionalization of acyl pyridinium salts SYNAPTIC PHARMACEUTICAL CORPORATION (US) 1995-09-26 US disclosed
EP-0369762-B1 Pesticides ROUSSEL UCLAF (FR) 1993-12-29 EP disclosed
EP-0516410-A2 Novel synthesis of 19-nor vitamin D compounds WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 1992-12-02 EP disclosed
EP-0369762-A1 Pesticides ROUSSEL-UCLAF (FR) 1990-05-23 EP disclosed