Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 18/20 | 0.44 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4756616 | 0.90 | TLR7 (0.40) | TLR7 | |
| SCHEMBL4758002 | 0.82 | TLR7 (0.46) | TLR7TLR8 | |
| SCHEMBL5412540 | 0.80 | TLR7 (0.36) | TLR7TLR8 | |
| SCHEMBL5415713 | 0.80 | LRRK2 (0.41) | — | |
| SCHEMBL5415664 | 0.79 | TLR7 (0.45) | TLR7TLR8 | |
| SCHEMBL5413507 | 0.77 | ALOX5 (0.44) | TLR7 | |
| SCHEMBL5405214 | 0.72 | TLR7 (0.43) | TLR7TLR8HTT | |
| SCHEMBL4758005 | 0.72 | TLR7 (0.45) | TLR7TLR8 | |
| SCHEMBL14594198 | 0.71 | TLR7 (0.49) | TLR7TLR8 | |
| SCHEMBL4757171 | 0.67 | TLR7 (0.61) | TLR7TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7163947-B2 | 1-Amino 1H-imidazoquinolines | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2007-01-16 | — | — | US | disclosed |
| WO-2006028451-A1 | 1-AMINO 1-H-IMIDAZOQUINOLINES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2006-03-16 | — | — | WO | disclosed |
| US-20050054640-A1 | 1-Amino 1H-imidazoquinolines | 3M INNOVATIVE PROPERTIES COMPANY | 2005-03-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050054640-A1 | 1-Amino 1H-imidazoquinolines | IL2, IFNG, IL4I1 | TLR7 146/4885TLR8 507/4885HTT 3823/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.