Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.36 |
| ▸ | TACR2 | P21452 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5397657 | 1.00 | DNM1 (0.40) | DNM1MEN1KMT2ATP53MAPK1 | |
| SCHEMBL27793173 | 1.00 | DNM1 (0.40) | DNM1MEN1KMT2ATP53MAPK1 | |
| SCHEMBL5389470 | 1.00 | DNM1 (0.40) | DNM1MEN1KMT2ATP53MAPK1 | |
| SCHEMBL18660546 | 1.00 | DNM1 (0.40) | DNM1MEN1KMT2ATP53MAPK1 | |
| SCHEMBL5388357 | 1.00 | DNM1 (0.40) | DNM1MEN1KMT2ATP53MAPK1 | |
| SCHEMBL5393997 | 1.00 | DNM1 (0.40) | DNM1MEN1KMT2ATP53MAPK1 | |
| SCHEMBL5389878 | 1.00 | DNM1 (0.40) | DNM1MEN1KMT2ATP53MAPK1 | |
| SCHEMBL5394695 | 1.00 | DNM1 (0.40) | DNM1MEN1KMT2ATP53MAPK1 | |
| Water SCHEMBL10945410 | 0.98 | HTT (0.41) | DNM1MEN1KMT2ATP53MAPK1 | |
| Hydrochloric Acid SCHEMBL28979756 | 0.98 | DNM1 (0.39) | DNM1MEN1KMT2ATP53MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990674-A | Synthesis of aliphatic aromatic phosphine oxides | OCCIDENTAL CHEMICAL CORPORATION (US) | 1991-02-05 | — | — | US | claimed |
| CN-103068807-B | By using the preparation method of phenyl substituted heterocycle derivative of coupling process of palladium compound | TEIJIN PHARMA LTD. (JP) | 2016-05-25 | — | — | CN | disclosed |
| CN-105506284-A | Lanthanide extraction system, extraction method and application thereof | UNIV HUBEI SCIENCE & TECH | 2016-04-20 | — | — | CN | disclosed |
| CN-103068807-A | Method for producing phenyl-substituted heterocyclic derivative by means of coupling method using a palladium compound | TEIJIN PHARMA LTD | 2013-04-24 | — | — | CN | disclosed |
| CN-102333765-A | Process for producing phenyl-substituted heterocyclic derivative through coupling using transition metal catalyst | TEIJIN PHARMA LTD | 2012-01-25 | — | — | CN | disclosed |
| US-7214747-B2 | Phosphorus substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2007-05-08 | — | — | US | disclosed |
| US-20050239980-A1 | Phosphorus substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. | 2005-10-27 | — | — | US | disclosed |
| CN-1046936-C | Process for the carbonylation of an acelylenically unsaturated compound | ICI LTD (GB) | 1999-12-01 | — | — | CN | disclosed |
| EP-0686063-A1 | A METHOD FOR SEPARATING CATALYST FROM A HYDROFORMYLATION REACTION PRODUCT USING ALKYLATED LIGANDS | EXXON CHEMICAL PATENTS INC. (US) | 1995-12-13 | — | — | EP | disclosed |
| WO-1994019104-A1 | A METHOD FOR SEPARATING CATALYST FROM A HYDROFORMYLATION REACTION PRODUCT USING ALKYLATED LIGANDS | EXXON CHEMICAL PATENTS INC. (US) | 1994-09-01 | — | — | WO | disclosed |
| US-4990674-A | Synthesis of aliphatic aromatic phosphine oxides | OCCIDENTAL CHEMICAL CORPORATION (US) | 1991-02-05 | — | — | US | disclosed |
| EP-0404250-A2 | Preparation of N,N-dialkylcarbamoylmethylphosphine oxide | AKZO N.V. (NL) | 1990-12-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050239980-A1 | Phosphorus substituted metallocene compounds for olefin polymerization | CCRL2, ARL1, OSBP2 | DNM1 3790/4885MEN1 1786/4885KMT2A 3569/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.