Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NPY1R | P25929 | 1/20 | 0.38 |
| ▸ | PTPRA | P18433 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HRH2 | P25021 | 1/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5406749 | 0.82 | EPHX2 (0.43) | EPHX2SMN1; SMN2RAB9ALMNA | |
| SCHEMBL5405591 | 0.75 | PTPRA (0.42) | EPHX2SMN1; SMN2CA12CA1CA2 | |
| SCHEMBL5413350 | 0.74 | NPC1 (0.46) | SMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL5414559 | 0.74 | SMN1; SMN2 (0.47) | SMN1; SMN2LMNA | |
| SCHEMBL14066327 | 0.74 | GRIN2D (0.55) | EPHX2CA12CA1CA2CA9 | |
| SCHEMBL5410214 | 0.72 | SLC6A4 (0.42) | — | |
| SCHEMBL5403135 | 0.72 | MTNR1A (0.46) | EPHX2SMN1; SMN2MEN1KMT2AHPGD | |
| SCHEMBL5407587 | 0.71 | SLC6A4 (0.48) | CYP1A2CYP2C19 | |
| SCHEMBL5401748 | 0.71 | SLC6A4 (0.48) | CYP1A2CYP2C19 | |
| SCHEMBL7526215 | 0.70 | EPHX2 (0.40) | EPHX2SMN1; SMN2CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7247645-B2 | Dihydropyridine derivatives | AJINOMOTO CO., INC. (JP) | 2007-07-24 | — | — | US | disclosed |