Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5405595 | 0.82 | EPHX2 (0.41) | EPHX2LMNASMN1; SMN2RAB9A | |
| SCHEMBL5414559 | 0.78 | SMN1; SMN2 (0.47) | LMNASMN1; SMN2 | |
| SCHEMBL5413350 | 0.75 | NPC1 (0.46) | LMNASMN1; SMN2RAB9A | |
| SCHEMBL5406745 | 0.74 | EPHX2 (0.41) | EPHX2LMNAGAASMN1; SMN2LTA4H | |
| SCHEMBL5410214 | 0.73 | SLC6A4 (0.42) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5403135 | 0.73 | MTNR1A (0.46) | EPHX2SMN1; SMN2 | |
| SCHEMBL5407587 | 0.72 | SLC6A4 (0.48) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5401748 | 0.72 | SLC6A4 (0.48) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL1505920 | 0.71 | SIGMAR1 (0.54) | LMNASMN1; SMN2LTA4HRAB9ASLC6A2 | |
| SCHEMBL10757568 | 0.69 | SMN1; SMN2 (0.43) | LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7247645-B2 | Dihydropyridine derivatives | AJINOMOTO CO., INC. (JP) | 2007-07-24 | — | — | US | disclosed |