Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 3/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | CNR1 | P21554 | 4/20 | 0.43 |
| ▸ | CNR2 | P34972 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | CASR | P41180 | 3/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5413350 | 0.78 | NPC1 (0.46) | TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL5414559 | 0.75 | SMN1; SMN2 (0.47) | MTNR1AMTNR1BCNR1CNR2TSHR | |
| SCHEMBL5410941 | 0.75 | MTNR1A (0.46) | MTNR1AMTNR1BCNR1CNR2CASR | |
| SCHEMBL5410214 | 0.73 | SLC6A4 (0.42) | CASR | |
| SCHEMBL5406749 | 0.73 | EPHX2 (0.43) | EPHX2SMN1; SMN2 | |
| SCHEMBL5405595 | 0.72 | EPHX2 (0.41) | KMT2AMEN1EPHX2HPGDALOX15 | |
| SCHEMBL5401748 | 0.72 | SLC6A4 (0.48) | TSHRCYP3A4 | |
| SCHEMBL5407587 | 0.72 | SLC6A4 (0.48) | TSHRCYP3A4 | |
| SCHEMBL28970084 | 0.70 | MTNR1A (0.53) | MTNR1AMTNR1BKMT2ACNR1CNR2 | |
| SCHEMBL7114570 | 0.70 | PTGS2 (0.47) | MTNR1AMTNR1BKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7247645-B2 | Dihydropyridine derivatives | AJINOMOTO CO., INC. (JP) | 2007-07-24 | — | — | US | disclosed |