Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL540935 | 0.83 | ALDH1A1 (0.41) | ALDH1A1NPC1PLA2G1BNFKB1CASP3 | |
| Hydrochloric Acid SCHEMBL31356224 | 0.79 | ALDH1A1 (0.41) | ALDH1A1NPC1PLA2G1BNFKB1CASP3 | |
| Hydrochloric Acid SCHEMBL540419 | 0.79 | ALDH1A1 (0.41) | ALDH1A1NPC1PLA2G1BNFKB1CASP3 | |
| Hydrochloric Acid SCHEMBL8853890 | 0.79 | ALDH1A1 (0.41) | ALDH1A1NPC1PLA2G1BNFKB1CASP3 | |
| Hydrochloric Acid SCHEMBL541054 | 0.79 | ALDH1A1 (0.41) | ALDH1A1NPC1PLA2G1BNFKB1CASP3 | |
| Hydrochloric Acid SCHEMBL5086021 | 0.79 | ALDH1A1 (0.41) | ALDH1A1NPC1PLA2G1BNFKB1CASP3 | |
| SCHEMBL30719677 | 0.78 | DYRK1A (0.52) | ALDH1A1NPC1PLA2G1BNFKB1CASP3 | |
| SCHEMBL1538379 | 0.78 | ALDH1A1 (0.44) | ALDH1A1NPC1PLA2G1BNFKB1CASP3 | |
| SCHEMBL30438243 | 0.78 | ALDH1A1 (0.44) | ALDH1A1NPC1PLA2G1BNFKB1CASP3 | |
| SCHEMBL9754019 | 0.78 | ALDH1A1 (0.44) | ALDH1A1NPC1PLA2G1BNFKB1CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110494458-B | Alumoxane-activated metallocene catalysts | 博里利斯股份公司 | 2023-08-15 | — | — | CN | claimed |
| CN-110234665-B | Catalyst system for preparing polyethylene copolymers in high temperature solution polymerization process | 博里利斯股份公司 | 2022-05-24 | — | — | CN | claimed |
| CN-101679556-B | Super-solution homogeneous propylene polymerization | EXXON MOBIL CHEM PATENTS INC | 2012-06-06 | — | — | CN | claimed |
| CN-114437261-B | Olefin polymerization metallocene catalyst and preparation method and application thereof | 中国石油化工股份有限公司 | 2024-03-26 | — | — | CN | disclosed |
| CN-113906059-B | Catalyst system | 博里利斯股份公司 | 2024-03-12 | — | — | CN | disclosed |
| CN-117377700-A | Plastomer with fast crystallization rate | 诺瓦化学品(国际)股份有限公司 | 2024-01-09 | — | — | CN | disclosed |
| CN-117222523-A | biaxially oriented film | 诺瓦化学品(国际)股份有限公司 | 2023-12-12 | — | — | CN | disclosed |
| CN-117015463-A | high density polyethylene composition | 诺瓦化学品(国际)股份有限公司 | 2023-11-07 | — | — | CN | disclosed |
| CN-116964111-A | Very low density polyethylene with fast crystallization rate | 诺瓦化学品(国际)股份有限公司 | 2023-10-27 | — | — | CN | disclosed |
| CN-112368306-B | Polyethylene composition and film having high rigidity, excellent sealability and high permeability | 诺瓦化学品(国际)股份有限公司 | 2023-10-20 | — | — | CN | disclosed |
| CN-116917404-A | bimodal polyethylene composition | 诺瓦化学品(国际)股份有限公司 | 2023-10-20 | — | — | CN | disclosed |
| EP-1614699-B9 | PROPYLENE COPOLYMER, POLYPROPYLENE COMPOSITION, USE THEREOF, TRANSITION METAL COMPOUNDS, AND CATALYSTS FOR OLEFIN POLYMERIZATION | MITSUI CHEMICALS INC (JP) | 2009-12-16 | — | — | EP | disclosed |
| US-7452946-B2 | copolymer with C3 to C10 alpha -olefin; provides a blow-molded product and an extrusion-molded product excellent in moldability, mechanical strength and outward appearance; produced in the presence of a solid catalyst | MITSUI CHEMICALS, INC. (JP) | 2008-11-18 | — | — | US | disclosed |
| EP-1988104-A1 | Propylene copolymer, polypropylene composition, use thereof, transition metal compounds, and catalysts for olefin polymerization | Mitsui Chemicals, Inc. (JP) | 2008-11-05 | — | — | EP | disclosed |
| EP-1985637-A1 | Propylene copolymer, polypropylene composition, use thereof, transition metal compounds, and catalysts for olefin polymerization | Mitsui Chemicals, Inc. (JP) | 2008-10-29 | — | — | EP | disclosed |
| EP-1985638-A1 | Propylene copolymer, polypropylene composition, use thereof, transition metal compounds, and catalysts for olefin polymerization | Mitsui Chemicals, Inc. (JP) | 2008-10-29 | — | — | EP | disclosed |
| EP-1614699-B1 | PROPYLENE COPOLYMER, POLYPROPYLENE COMPOSITION, USE THEREOF, TRANSITION METAL COMPOUNDS, AND CATALYSTS FOR OLEFIN POLYMERIZATION | MITSUI CHEMICALS INC (JP) | 2008-10-15 | — | — | EP | disclosed |
| US-20060199925-A1 | Ethylene polymer | MITSUI CHEMICALS, INC. (JP) | 2006-09-07 | — | — | US | disclosed |
| EP-1632505-A1 | ETHYLENE POLYMER | Mitsui Chemicals, Inc. (JP) | 2006-03-08 | — | — | EP | disclosed |
| EP-1614699-A1 | PROPYLENE COPOLYMER, POLYPROPYLENE COMPOSITION, USE THEREOF, TRANSITION METAL COMPOUNDS, AND CATALYSTS FOR OLEFIN POLYMERIZATION | Mitsui Chemicals, Inc. (JP) | 2006-01-11 | — | — | EP | disclosed |